Table 2 The serum levels of HE4 and CA125 and ROMA values in the examined groups
| Â | Benign ovarian diseases | Epithelial ovarian cancer | p-value |
|---|---|---|---|
Median (range) | Median (range) | ||
all patients | |||
HE4 (pmol/l) | 53.4 (22.1–328.6) | 118.4 (37.4–1921.4) | <0.001 |
CA125 (U/ml) | 19.4 (4.2–150.3) | 116.3 (14.4–3798.4) | <0.001 |
ROMA (%) | 12.4 (0.8–42.6) | 50.4 (21.8–99.1) | <0.001 |
premenopausal | |||
HE4 (pmol/l) | 50.4 (22.1–98.4) | 84.1 (37.4–762.4) | <0.001 |
CA125 (U/ml) | 23.3 (4.2–150.3) | 75.4 (14.4–706.2) | <0.001 |
ROMA (%) | 10.2 (0.8–35.8) | 28.6 (21.8–85.6) | <0.001 |
postmenopausal | |||
HE4 (pmol/l) | 56.4 (32.8–328.6) | 147.8 (54.9–1921.4) | <0.001 |
CA125 (U/ml) | 12.3 (9.4–113.3) | 168.7 (15.9–3798.4) | <0.001 |
ROMA (%) | 14.6 (1.2–42.6) | 72.2 (30.2–99.1) | <0.001 |