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Table 2 Results of immunohistochemistry and description of MMP-14/CD44 co-expression group

From: MMP-14 and CD44 in Epithelial-to-Mesenchymal Transition (EMT) in ovarian cancer

  Early-stage (n = 23) Advanced-stage (n = 74) p value*
MMP-14 Overall Score (number of patients)    0.07
 0 8 11  
 1 10 42  
MMP-14 stroma (number of patients)    0.03
no 4 25  
weak 14 23  
strong 0 5  
CD 44 Overall Score    0
 0 6 47  
 1 15 21  
E-cadherin Overall Score    n.s.
 0 0 1  
 1 21 67  
Vimentin epithelial score 30 % 32 % n.s.
Group with co-expression MMP-14-CD44a 5 14  
Histological subtype
 Serous 1 9  
 Mucinous 1 1  
 Endometroid 1 0  
 Clear cell 2 1  
 Adenocarcinoma unspecified 0 2  
 Mixed 0 1  
Grade
 Low-grade 1 3  
 High-grade 4 11  
Debulking
 Complete   11  
 Incomplete   3  
E-cadherin Overall Score
 0 0 1  
 1 5 13  
Vimentin epithelial score 36 % 34 %  
  1. *p value based on T-test and chi-square between early-stage and advanced-stage when appropriate
  2. anumbers too small for statistical analysis, n.s. not significant