Skip to main content

Table 2 Results of immunohistochemistry and description of MMP-14/CD44 co-expression group

From: MMP-14 and CD44 in Epithelial-to-Mesenchymal Transition (EMT) in ovarian cancer

 

Early-stage (n = 23)

Advanced-stage (n = 74)

p value*

MMP-14 Overall Score (number of patients)

  

0.07

 0

8

11

 

 1

10

42

 

MMP-14 stroma (number of patients)

  

0.03

no

4

25

 

weak

14

23

 

strong

0

5

 

CD 44 Overall Score

  

0

 0

6

47

 

 1

15

21

 

E-cadherin Overall Score

  

n.s.

 0

0

1

 

 1

21

67

 

Vimentin epithelial score

30 %

32 %

n.s.

Group with co-expression MMP-14-CD44a

5

14

 

Histological subtype

 Serous

1

9

 

 Mucinous

1

1

 

 Endometroid

1

0

 

 Clear cell

2

1

 

 Adenocarcinoma unspecified

0

2

 

 Mixed

0

1

 

Grade

 Low-grade

1

3

 

 High-grade

4

11

 

Debulking

 Complete

 

11

 

 Incomplete

 

3

 

E-cadherin Overall Score

 0

0

1

 

 1

5

13

 

Vimentin epithelial score

36 %

34 %

 
  1. *p value based on T-test and chi-square between early-stage and advanced-stage when appropriate
  2. anumbers too small for statistical analysis, n.s. not significant