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Table 1 Patient characteristics

From: Serum CA125 and HE4 levels as predictors for optimal interval surgery and platinum sensitivity after neoadjuvant platinum-based chemotherapy in patients with advanced epithelial ovarian cancer

Characteristics

Overall population (n = 20)

CC-0 (n = 16)

CC-1+ (n = 14)

p-value

Relapse < 6 months (n = 12)

Relapse > 6 months (n = 18)

p-value

Age (years)

62.8 +/− 10.77

63.62 +/− 8.62

61.93 +/− 13.09

0.92

63.57 +/− 11.95

62.2 +/− 9.97

0.63

BMI (kg/m2)

23.64 +/− 3.39

23.69 +/− 2.91

23.59 +/− 3.98

0.77

22.75 +/− 3.04

24.42 +/− 3.58

0.24

Gestity

1.81 +/− 1.49

1.94 +/− 1.95

1.64 +/− 1.69

0.45

1.23 +/− 1.47

1.80 +/− 1.57

0.90

Parity

1.74 +/− 1.65

1.75 +/− 1.24

1.73 +/− 2.20

0.51

1.92 +/− 1.98

1.60 +/− 1.40

0.86

Menopause

27 (90 %)

15 (93.7 %)

12 (85.7 %)

0.59

10 (83.3 %)

17 (94.4 %)

0.59

FIGO stage

   

1

  

0.63

 IIIa

1 (3.31 %)

1 (6.25 %)

0

 

0

1 (5.55 %)

 

 IIIb

1 (3.31 %)

1 (6.25 %)

0

 

0

1 (5.55 %)

 

 IIIc

23 (76.7 %)

12 (75 %)

11 (78.6 %)

 

9 (75 %)

14 (77.8 %)

 

 IV

5 (16.67 %)

2 (12.5 %)

3 (21.4 %)

 

3 (25 %)

2 (11.1 %)

 

Grading

   

0.26

  

0.63

 I

3 (10 %)

3 (18.7 %)

0

 

0

3 (16.7 %)

 

 II

9 (30 %)

5 (31.3 %)

4 (35.7 %)

 

5 (41.7 %)

4 (22.2 %)

 

 III

15 (50 %)

6 (37.5 %)

9 (64.3 %)

 

5 (41.7 %)

10 (55.6 %)

 

Pre-NAC CA-125 (UI/ml)

1762.63 [16–9453]

1432.89 [16–9453]

2257.25 [302–9400]

0.05

1884.07 [16–9453]

1656.8 [57–9400]

0.15

Pre-NAC HE4 (pmol/l)

985.3 [46.1–6562]

928.22 [46.1–6562]

984.26 [153.2–2746]

0.24

1374.59 [63.9–6562]

644.66 [46.1–2031]

0.13

Cycles of NAC

5.75 [3–7]

5.5 [3–6]

6.12 [6–7]

0.08

5.60 [3–7]

5.62 [4–6]

0.69

  1. CC-0 non residual disease after interval debulking surgery (IDS), CC-1+ residual disease after IDS
  2. BMI body mass index, FIGO International Federation of Gynecology and Obstetrics, NAC neoadjuvant chemotherapy