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Table 2 Tumour markers after the 3rd cycle of NAC and the interval surgery outcome (a) or first relapse (b)

From: Serum CA125 and HE4 levels as predictors for optimal interval surgery and platinum sensitivity after neoadjuvant platinum-based chemotherapy in patients with advanced epithelial ovarian cancer

(a)

 

CC-0 (n = 16)

CC-1+ (n = 14)

p-value

CA125 ≤ 75 UI/ml

13 (81.3 %)

2 (12.3 %)

0.0007

HE4 ≤ 252 pmol/l

14 (87.5 %)

6 (42.8 %)

0.02

CA125 ≤ 75 UI/ml and HE4 ≤ 252 pmol/l

15 (93.7 %)

1 (7.1 %)

0.00001

(b)

 

Relapse < 6 months (n = 12)

Relape > 6 months (n = 18)

p-value

CA125 ≤ 35 UI/ml

1 (8.3 %)

10 (55.5 %)

0.018

HE4 ≤ 115 pmol/l

1 (8.3 %)

13 (72.2 %)

0.0017

CA125 ≤ 35 UI/ml and HE4 ≤ 115 pmol/l

1 (8.3 %)

13 (72.2 %)

0.0017