Table 2 Clinical Factors by SNCG expression status
SNCG positive | SNCG negative | p-value | |
|---|---|---|---|
No. of patients (n = 357) | 257 (72 %) | 100 (28 %) | |
Age, year | |||
Median | 63.0 | 63.5 | 0.93 |
Range | 22–91 | 36–93 | |
CA125 level | |||
≤ 485 | 93 (48.7 %) | 48 (64.9 %) | 0.02 |
> 485 | 98 (51.3 %) | 26 (35.1 %) | |
Ascites | |||
No | 44 (24.4 %) | 29 (40.8 %) | 0.01 |
Present | 136 (75.6 %) | 42 (59.2 %) | |
Debulking Status | |||
Optimal | 169 (78.6 %) | 76 (92.7 %) | 0.004 |
Suboptimal | 46 (21.4 %) | 6 (7.3 %) | |
Stage | |||
I/II | 30 (12.2 %) | 34 (36.6 %) | <0.0001 |
III/IV | 215 (87.8 %) | 59 (63.4 %) | |
Primary Site of Disease | |||
Ovarian | 219 (85.9 %) | 81 (81.0 %) | 0.28 |
Primary Peritoneal | 34 (13.3 %) | 19 (19.0 %) | |
Fallopian Tube | 2 (0.8 %) | 0 (0.0 %) | |
Histologic subtype | |||
Serous | 181 (82.7 %) | 31 (38.3 %) | <0.0001 |
Non-serous | 38 (17.3 %) | 50 (61.7 %) | |
Grade (FIGO) | |||
1/2 | 11 (5.8 %) | 12 (16.0 %) | 0.01 |
3 | 177 (94.2 %) | 63 (84.0 %) | |
Recurrence | |||
No | 23 (19.49 %) | 15 (29.41 %) | 0.17 |
Yes | 95 (80.51 %) | 36 (70.59 %) | |
Status | |||
Alive | 60 (23.3 %) | 29 (29.0 %) | 0.28 |
Dead | 197 (76.7 %) | 71 (71.0 %) | |