From: Salpingectomy before assisted reproductive technologies: a systematic literature review
Authors & Years | Type of Study | Patients (total) | Patients (Salpingectomy) | Patients-Controls | Age (year ± SD) | BMI (± SD) | Indication for Surgery | Time from Surgery | Reason of Infertility | Duration of Infertility |
---|---|---|---|---|---|---|---|---|---|---|
Lass et al. [1] | OP | 102 | a) 29 SLP (ECP) Type: unilateral Surgery: not specified | b) 73 no surgery (healthy subjects) | a) 33.1 ± 4.9 b) 34.2 ± 4.1 | n.r | a) ECP | 2 years | a,b) MF 31; ID 42 | 2 years after surgery at least |
Dechaud et al. [2] | RCT | 60 | a) 30 SLP (HY) Type: not specified Surgery: LPS | b) 30 diagnostic LPS (TF, HY) | a) 31.7 ± 4.5 b) 30.6 ± 3.3 | n.r | a,b) salpingitis or HY | a) 10.1 ± 7.5 months b) 9.5 ± 7.2 months (LPS diagnostic) | a,b) TF | a) 55.2 ± 33.3 months b) 48 ± 25.4 months |
Bredkjaer et al. [3] | R | 278 | a) 139 SLP (HY) Type: 128 bilateral, 11partial Surgery: not specified | b) 139 no surgery (TF, no HY) | a) 32.6 (22–39) b) 32.9 (24–40) | n.r | a) HY | 92 pz between 1.5 and 5 years 47 pz 3–6 months | a,b) TF | n.r |
Strandell et al. [4] | RCT | 204 | a) 116 SLP (HY) Type: not specified Surgery: LPS | b) 88 no surgery (TF, HY) | a) 31.8 ± 3.6 b) 31.8 ± 3.7 | n.r | a,b) HY uni o bilateral | 2 months (at least) | a,b) TF | 1 month to 2 years |
Dar et al. [5] | R | 26 | a) 26 SLP (ECP) Type : 25 unilateral, 1 bilateral Surgery: LPS | Control: same patients before surgery | a) 31.7 ± 3.6 | n.r | a) ECP | a period < 3 years between the cycles (before and after surgery) | a) MEF 16; MF 6 AN 1; END 1; ID 2 | n.r |
Strandell et al. [6] | OP | 26 | a) 26 SLP (HY) Type: 9 unilateral and 17 bilateral Surgery: LPS | Control: same patients before surgery | a) 32.7 ± 3.6 | n.r | a) HY | n.r | n.r | n.r |
Strandell et al. [7] | RCT | 185 | a) 103 SLP (HY) Type: 40 unilateral, 63 bilateral Surgery: LPS | b) 82 no surgery (TF, HY) | a) 32.8 ± 3.5 b) 32.5 ± 3.8 | n.r | a) HY | n.r | a,b) TF | n.r |
Surrey et al. [8] | R | 94 | a) 32 SLP (HY) Type: not specified Surgery: LPS | b) 15 PTO (HY) c) 35 no surgery (TF no HY) d) 12 tubal ligation (prior sterilization) | a) 35.1 ± 0.7 b) 35.4 ± 1.0 c) 35.6 ± 0.7 d) 38.2 ± 1.0 | n.r | a,b) HY c,d) TF | 6 months | a,b,c,d) TF | n.r |
Tal et al. [12] | OP | 78 | a) 26 SLP (ECP) Type: unilateral Surgery: 14 LPT, 12 LPS | b) 52 no surgery (healthy subjects) | a) 32.1 ± 4.1 b) 32.0 ± 5.1 | n.r | a) ECP | 1-9 years | n.r | n.r |
Chan et al. [13] | R | 32 | 32 SLP (ECP) a) 18 unilateral LPS b) 14 unilateral LPT | Controls: non-operated site | a) 34 (31–38) b) 36 (33–44) | a) 20.96 b) 21.44 | a,b) ECP | 3 months (at least) | n.r | n.r |
Kontoravdis et al. [9] | RCT | 115 | a) 50 POT (HY) b) 50 SLP (HY) Type: not specified Surgery: LPS | c) 15 no surgery (HY) | a) 31 ± 4.5 b) 29.8 ± 3.4 c) 34 ± 5.3 | n.r | a,b) HY unilateral or bilateral | n.r | n.r | n.r |
Gelbaya et al. [6] | R | 168 | a) 40 SLP (HY) Type: 16 unilateral, 24 bilateral b) 25 PTD Type: 9 unilateral, 16 bilateral Surgery: LPS | c) 103 no surgery (tubal factor, no HY) | a) 32.8 ± 3.57 b) 33.1 ± 2.71 c) 33.5 ± 3.32 | n.r | a,b) HY | 3 months at least | All TF plus: a) MF 2/40; OF 4/40; END 2/40 b) MF 5/25;OF 5/25; END 1/25 c) MF 12/103; OF 9/103; END 5/103 | n.r |
Moshin & Hotineanu [11] | RCT | 204 | a) 60 SLP (HY) b) 78 PTO (HY) Type: not specified Surgery: not specified | c) 66 no surgery (HY) | n.r | n.r | a,b) HY | n.r | n.r | n.r |
Sezik et al. [16] | RCT | 24 | a) 12 total hysterectomy + bilateral- SLP Surgery: LPT | b) 12 total hysterectomy without SLP | a) 41.6 ± 1.7 b) 41.1 ± 1.4 | a) 24.5 ± 2.2 b) 26.6 ± 4.8 | n.r | n.r | n.r | n.r |
Nakagawa et al. [17] | P | 17 | a) 6 SLP (HY) Type: not specified Surgery: LPS | b) 11 PTD (HY) | a) 31.7 ± 6.3 b) 35.3 ± 3.6 | n.r | a,b) HY | n.r | n.r | n.r |
Orvieto et al. [18] | R | 15 | a) 15 SLP (HY) Type: not specified Surgery: not specified | Controls: same patients before surgery | a) 32 ± 4.4 | 24 ± 5.5 | a) HY | n.r | n.r | n.r |
Almog et al. [19] | R | 36 | a) 36 SLP Type :22 unilateral, 14 bilateral Surgery: LPS | Controls: same patients before surgery | a) 34.2 ± 4.5 | n.r | a) ECP 21 HY 14 Both 1 | 152 ± 36 days | n.r | n.r |
Xi et al. [20] | R | 156 | a) 76 SLP (ECP) Type: 32 bilateral, 44 unilateral (23 controlateral ligation) Surgery: LPS | Controls: same patients before surgery b) 80 no surgery (healthy subjects) | a) 31.5 ± 4.2 | n.r | a) ECP | At least 3 months after salpingectomy | a) TF 54 MF 7 END 5 | n.r |
Na et al. [21] | R | 97 | a) 41 SLP (HY) Type: not specified Surgery: LPS | b) 56 sclerotherapy (HY) | a) 32.4 ± 4.5 b) 32.9 ± 4.1 | a) 22.2 ± 5.0 b) 21.5 ± 2.2 | a, b) HY | n.r | a,b) HY | a) 3.8 ± 3.4 b) 2.9 ± 1.8 |
Ni et al.[22] | PC | 134 | 60 SLP a) 26 bilateral b) 34 unilateral c) 23 PTO Surgery: LPS | d) 51 no surgery (TF, no HY) | a) 29.23 ± 2.98 b) 30.12 ± 3.73 c) 30.65 ± 3.32 d) 29.18 ± 3.36 | a) 21.21 ± 2.05 b) 21.37 ± 1.89 c) 20.78 ± 2.04 d) 20.95 ± 1.66 | a, b) ECP, HY c) HY | n.r | TF n.s | a) 2.00 ± 1.67 years b) 3.14 ± 2.12 c) 4.61 ± 2.81 d) 3.98 ± 2.44 |
Uyar et al. [23] | OP | 162 | a) 33 patients (ECP) - 26 unilateral SLP - 3 salpingostomy - 1 tubal milkink - 1 fimbriectomy - 2 tubal abortion surgery: LPS/LPT | b) 49 MTX (ECP) c) 80 no surgery | a) 31.1 ± 5.1 b) 29.7 ± 5.0 c) 28.9 ± 6.0 | n.r | a, b) ECP | n.r | n.r | n.r |
Lin et al. [24] | R | 288 cycles in 251 women | a) 103 cycles in 96 SLP Type: not specified Surgery: LPS | b) 185 cycles in 155 women (prior sterilization, tuboplasty, PTO) TF infertility | a) 33.2 ± 4.2 b) 32.8 ± 4.6 | a) 22.1 ± 4.3 b) 21.9 ± 3.2 | a) ECP or HY | n.a | a,b) TF | n.a |
Grynnerup et al. [25] | P-CS | 71 | a) 16 SLP (HY) Type: (uni/ bilateral) not specified Surgery: LPS | b) 42 no surgery (TF, with or without HY) c) 13 no surgery (unexplained infertility, no HY) | a) 34 (25–37) b) 33 (26–37) c) 32 (27–36) | n.r | a) HY | At least 2 months | a) HY 16 b) TF 42 c) ID 13 | a) 5 years b) 4 years c) 5 years |
Findley et al. [26] | RCT | 30 | a) 15 hysterectomy + bilateral SLP Surgery: LPS | b) 15 hysterectomy with no SLP LPS | a) 36.6 ± 4.5 b) 37.8 ± 5.0 | a) 34.4 ± 6.8 b) 38.1 ± 10.7 | a,b) benign indications | n.r | n.r | n.r |
Hill et al. [27] | R | 189 | a) 36 SLP (ECP) Type: unilateral Surgery: not specified | Controls: same patients before surgery b) 153 MTX (ECP) | a) 35.8 ± 4.3 b) 34.3 ± 4.5 | n.r | a,b) ECP | n.r | n.r | n.r |
Ye et al. [28] | R | 198 | 124 SLP (HY, ECP, TOA) a) 83 unilateral b) 41 bilateral Surgery: not specified | c) 74 no surgery (infertility, no TF) | a) 33,02 ± 4,66 b) 33,58 ± 3,95 c) 33,8 ± 4,67 | a) 21,63 ± 2,46 b) 21,1 ± 2,85 c) 21,43 ± 2,83 | a) ECP 79 HY 3 TOA 1 b) ECP 24 HY 16 TOA 1 | n.r | a) MF 45; MF & FF 28 b) MF 16 MF & FF 15 c) MF 38 MF & FF 26 UNKNOWN 2 | a) 0.31 ± 1.13 PI 2.85 ± 2.81 SI b) 0.82 ± 1.96 PI 3.23 ± 3.24 SI c) 3.6 ± 4.15 PI 2.36 ± 3.32 SI |
Pereira et al. [29] | R | 144 | a) 37 SLP (ECP) Type: unilateral Surgery: LPS b) 107 MTX (ECP) | Controls: same patients before surgery or MTX | a) 36.4 ± 3.03 b) 37.1 ± 4.01 | a) 24 ± 3.65 b) 23.2 ± 4.23 | a,b) ECP | 12 months | a) A 31.8 %; TF 3 13.6 %; END 9 %; MF 18.1 %; ID 4.55 %; Other 18.1 % b) AN 32.9 %;TF 12.5 %: END 7.95 %; MF 23.9 % ID 5.68 % Other 15.9 % | n.r |
Odesjo et al. [30] | R | 153 | a) 118 SLP (ECP) Type: unilateral Surgery: not specified | b) 35 unilateral salpingotomy (ECP) | a) 32.5 ± 3.93 b) 33.8 ± 3.07 | a) 24.9 ± 4.5 b) 24 ± 3.76 | a,b) ECP | a) 3.11 ± 2.90 years b) 6.85 ± 5.05 years | a) TF 92 (78 %) a) other reasons 26 (22 %) b) TF 24 (70.6 %) b) other reason 10 (29.4 %) | n.r |
Venturella et al. [31] | RCT | 186 | a) 91 SLP standard b) 95 SLP wide* Type: bilateral surgery: LPS | Controls: same patients before surgery | a) 41.16 ± 5.33 b) 41.56 ± 5.45 | n.r | a,b) myomectomy, tubal surgical sterilization | n.a | n.a | n.a |