Pseudocarcinomatous hyperplasia | Adenocarcinoma |
---|---|
1. Most patients are usually younger. | 1. Most patients are postmenopausal, with a mean age of 62Â years |
2. It is always reactive and secondary. Usually associated with underlying chronic inflammation or hyperestrogenic states | 2. It is always primary. |
3. It shows no gross evidence of tumor, but there is inflamed, grossly dilated or thickened tube. | 3. Most carcinomas are grossly evident. |
4. Chronic inflammation is marked. | 4. Chronic inflammation is not prominent. |
5. Solid epithelial proliferation is not observed. | 5. Solid epithelial proliferation is variably evident. |
6. Mild to moderate nuclear atypia is observed | 6. Nuclear atypia is prominent. |
7. There are few mitotic figures. It has been considered an important criterion. | 7. There are numerous mitotic figures. |
8. Invasion of the tubal wall is not evident, but pseudoinvasion of the muscularis by gland like structures or lymphatic penetration by epithelial cells can be observed. | 8. True invasion of the tubal wall is evident. |