|
1. Most patients are usually younger.
|
1. Most patients are postmenopausal, with a mean age of 62 years
|
|
2. It is always reactive and secondary. Usually associated with underlying chronic inflammation or hyperestrogenic states
|
2. It is always primary.
|
|
3. It shows no gross evidence of tumor, but there is inflamed, grossly dilated or thickened tube.
|
3. Most carcinomas are grossly evident.
|
|
4. Chronic inflammation is marked.
|
4. Chronic inflammation is not prominent.
|
|
5. Solid epithelial proliferation is not observed.
|
5. Solid epithelial proliferation is variably evident.
|
|
6. Mild to moderate nuclear atypia is observed
|
6. Nuclear atypia is prominent.
|
|
7. There are few mitotic figures. It has been considered an important criterion.
|
7. There are numerous mitotic figures.
|
|
8. Invasion of the tubal wall is not evident, but pseudoinvasion of the muscularis by gland like structures or lymphatic penetration by epithelial cells can be observed.
|
8. True invasion of the tubal wall is evident.
|
