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Table 6 Effect of Rutin-I (100 mg/kg) and Rutin-II (150 mg/kg) on serum testosterone, estradioland progesterone concentrations in Letrozole induced PCOS rats after 36 days of experiment

From: Ameliorative effects of rutin against metabolic, biochemical and hormonal disturbances in polycystic ovary syndrome in rats

Hormonal concentrations Control PCOS Metformin Rutin-I Rutin-II
Testosterone (ng/ml) 1.88 ± 0.71 10.19 ± 0.76a*** 4.51 ± 0.30 b** 5.77 ± 0.68b* 8.21 ± 1.85a**
Estradiol (ng/ml) 19.41 ± 2.21 14.26 ± 2.70 28.57 ± 4.32 34.83 ± 8.26 27.25 ± 0.48
Progesterone (pg/ml) 43.43 ± 8.81 12.76 ± 3.75a** 22.98 ± 4.85 19.66 ± 5.34a* 24.63 ± 3.46
  1. Values are expressed as Mean ± SEM
  2. *=p< 0.05, **=p< 0.01, ***=p< 0.001
  3. aValue vs control, bValue vs PCOS