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Table 6 Effect of Rutin-I (100 mg/kg) and Rutin-II (150 mg/kg) on serum testosterone, estradioland progesterone concentrations in Letrozole induced PCOS rats after 36 days of experiment

From: Ameliorative effects of rutin against metabolic, biochemical and hormonal disturbances in polycystic ovary syndrome in rats

Hormonal concentrations

Control

PCOS

Metformin

Rutin-I

Rutin-II

Testosterone (ng/ml)

1.88 ± 0.71

10.19 ± 0.76a***

4.51 ± 0.30 b**

5.77 ± 0.68b*

8.21 ± 1.85a**

Estradiol (ng/ml)

19.41 ± 2.21

14.26 ± 2.70

28.57 ± 4.32

34.83 ± 8.26

27.25 ± 0.48

Progesterone (pg/ml)

43.43 ± 8.81

12.76 ± 3.75a**

22.98 ± 4.85

19.66 ± 5.34a*

24.63 ± 3.46

  1. Values are expressed as Mean ± SEM
  2. *=p< 0.05, **=p< 0.01, ***=p< 0.001
  3. aValue vs control, bValue vs PCOS