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Table 8 Effect of Rutin-I (100 mg/kg) and Rutin-II (150 mg/kg) on number of cystic follicles, atretic follicles and corpus luteum in Letrozole induced PCOS rats after 36 days of experiment

From: Ameliorative effects of rutin against metabolic, biochemical and hormonal disturbances in polycystic ovary syndrome in rats

Number of follicles Control PCOS Metformin Rutin-I Rutin-II
Cystic follicles 0.0 ± 0.0 10.17 ± 0.70a*** 5.16 ± 0.30a***b*** 6.16 ± 0.47 a***b*** 7.33 ± 0.42a***b**c*
Atreticfollicles 2.00 ± 0.25 4.50 ± 0.34a*** 2.83 ± 0.47b* 2.66 ± 0.33b* 2.83 ± 0.40b*
Corpousluteum 6.80 ± 0.37 2.40 ± 0.24a*** 4.20 ± 0.58a**b* 2.40 ± 0.50a*** c* 4.40 ± 0.24a**b*d*
  1. Values are expressed as Mean ± SEM
  2. *p< 0.05, **p< 0.01, ***p< 0.001
  3. aValue vs control, bValue vs PCOS, cValue vs Metformin, dValue vsRutin-I