Fig. 4

Spreading of cancer tissue by round vimentin-positive cells with diameters of 10–15 μm. In both the region of ovarian sections with early invasion of vimentin-positive cancer tissue (a–d) and region of later invasion with highly spread cancer tissue (e–h), the round vimentin-positive cells with diameters of 10–15 μm (arrows) were still present and were changing into the mesenchymal phenotype to possibly spread the cancer tissue. (Inverted microscope, magnifications 100x and 200x). Legend: brown-vimentin positivity and blue-nuclei after HE staining. Red Bar: 10 μm for h and 100 μm for a–g