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Table 3 Univariate and multivariate analysis of progression-free survival

From: Identification of factors that impact recurrence in patients with borderline ovarian tumors

Variables

 

Univariate

P

Multivariatea

P

HR

95% CI

HR

95% CI

Multiparous

Yes

0.32

0.15–0.67

0.024

   

Nulliparous

No

1

     

Diameter

≥10

0.26

0.09–0.70

0.0076

   

<10

1

     

Histology

Serous

1

     

Mucinous

0.41

0.18–0.95

0.0375

   

Endometrioid

0.64

0.19–2.19

0.4808

   

Micropapillary

Yes

3.88

1.76–8.52

0.0008

   

No

1

     

Stage

II & III

2.55

1.10–5.91

0.0295

   

I

1

     

Fertility preserving surgery

 USO

1.6

0.59–4.33

0.3553

1.26

0.37–4.08

0.7395

 USO + CC

5.74

2.10–15.67

0.0007

2.72

0.65–11.38

0.1719

 BC

5.89

2.25–14.42

0.0003

3.95

1.22–12.85

0.0223

Radical surgery

1

     

Invasive implant

Yes

4.87

1.67–14.20

0.0038

10.38

2.21–48.69

0.0030

No

1

     

Lymphadenectomy

Yes

0.44

0.21–0.94

0.0328

0.26

0.09–0.75

0.0129

No

1

     

Pelvic lymph node metastasis

Yes

4.34

1.21–15.67

0.0246

   

No

1

     

Para-aortic lymph node metastasis

Yes

17.34

1.80–167.50

0.0137

   

No

1

     

Chemotherapy

Yes

2.72

1.20–6.19

0.0164

   

No

      

Restaging

Yes

9.8

3.96–23.78

<0.0001

   

No

      
  1. USO unilateral salpingo-oophorectom, USO + CC unilateral salpingo-oophorectomy plus contralateral cystectomy, BC bilateral cystectomy
  2. aMultivariate model was built after controlling for tumor histology and stage