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Table 1 Serum and peritoneal fluid concentrations of sHLA-G, IL-10 and TNF-alpha in women with benign serous ovarian cysts, ovarian endometrioma and ovarian cancer (medians and interquartile ranges)

From: Serum and peritoneal fluid concentrations of soluble human leukocyte antigen, tumor necrosis factor alpha and interleukin 10 in patients with selected ovarian pathologies

Parameter

Serous cysts

(n = 54)

Endometrioma

(n = 43)

Ovarian cancer

(n = 38)

p

Serum sHLA-G (U/ml)

8.90 (5.35–21.75)

7.70 (5.15–17.00)

10.00 (5.47–14.40)

0.944

Peritoneal fluid sHLA-G (U/ml)

29.75 (15.63–51.70)

20.60 (15.80–37.54)

36.15 (20.68–62.08)

0.150

Serum IL-10 (pg/ml)

3.75* (3.20–11.20)

4.60* (4.20–6.65)

11.30 (4.60–21.00)

0.002

Peritoneal fluid IL-10 (pg/ml)

18.15#,§ (4.60–41.70)

53.00* (14.70–93.20)

128.80 (36.71–252.38)

<0.001

Serum TNF-alpha (pg/ml)

1.20# (1.00–1.73)

1.00# (0.73–1.68)

2.70 (1.90–4.00)

<0.001

Peritoneal fluid TNF-alpha (pg/ml)

1.80#,§ (1.00–3.80)

3.10 (1.70–17.50)

13.21 (8.35–25.35)

<0.001

  1. Significantly lower than in ovarian cancer patients: * p < 0.005, p < 0.001, # p < 0.0001; significantly lower than in endometrioma patients: § p < 0.005