Fig. 2

Overexpression of let-7e increases the sensitivity of ovarian cancer cell lines to cisplatin. a qRT-PCR analyses of let-7e expression in A2780, C13K and OV2008 after transfection with let-7e agomirs or inhibitors. b Cell viability was assessed by MTT assay after incubation with a series of cisplatin. c, d and e Clonogenic cell-survival assay analysis of cell viability after transfected with let-7e agomirs or inhibitors and treated with cisplatin. Representative images of colonies formed by A28780, C13K and OV2008 cell lines and the corresponding statistic graphs are shown. Student’s t-test, *P < 0.05, **P < 0.01