|
Clinicopathological Features
|
No. of Cases
|
Let-7e expression No.(%)
|
No. of Cases
|
BRCA1 expression No.(%)
|
Rad51 expression No.(%)
|
|---|
| | |
Low
|
High
|
P Value a
| |
Low
|
High
|
P Value a
|
Low
|
High
|
P Value a
|
|---|
|
Age at surgery, y
|
|
<50
|
25
|
10 (40.0)
|
15 (60.0)
|
1
|
26
|
11 (42.3)
|
15 (57.7)
|
0.800
|
11 (42.3)
|
15 (57.7)
|
0.126
|
|
≥50
|
40
|
15 (37.5)
|
25 (62.5)
| |
39
|
19 (48.7)
|
20 (51.3)
| |
25 (64.1)
|
14 (35.9)
| |
|
Histological subtypes
|
|
Serous
|
53
|
22 (41.5)
|
31 (58.5)
|
0.344
|
52
|
24 (46.2)
|
28 (53.8)
|
1
|
27 (51.9)
|
25 (48.1)
|
0.355
|
|
Others
|
12
|
3 (25.0)
|
9 (75.0)
| |
13
|
6 (46.2)
|
7 (53.8)
| |
9 (69.2)
|
4 (30.8)
| |
|
FIGO stage
|
|
I–II
|
17
|
5 (29.4)
|
12 (70.6)
|
0.563
|
18
|
9 (50.0)
|
9 (50.0)
|
0.784
|
13 (72.2)
|
5 (27.8)
|
0.104
|
|
III–IV
|
48
|
20 (41.7)
|
28 (58.3)
| |
47
|
21 (44.7)
|
26 (55.3)
| |
23 (48.9)
|
24 (51.1)
| |
|
Tumor categories
|
|
Type I
|
15
|
3 (20.0)
|
12 (80.0)
|
0.133
|
16
|
8 (50.0)
|
8 (50.0)
|
0.778
|
11 (68.7)
|
5 (31.3)
|
0.258
|
|
Type II
|
50
|
22 (44.0)
|
28 (56.0)
| |
49
|
22 (44.9)
|
27 (55.1)
| |
25 (51.0)
|
24 (49.0)
| |
|
Chemotherapy response
|
|
Sensitive
|
43
|
8 (18.6)
|
35 (81.4)
|
<0.0001
|
46
|
26 (56.5)
|
20 (43.5)
|
0.013
|
33 (71.7)
|
13 (28.3)
|
<0.0001
|
|
Resistant
|
22
|
17 (77.3)
|
5 (22.7)
| |
19
|
4 (21.1)
|
15 (78.9)
| |
3 (15.8)
|
16 (84.2)
| |
-
EOC epithelial ovarian cancer, FIGO International Federation of Gynecology and Obstetrics
-
a Fisher exact test
