|  | PFS a | OS a | Case No. (%) | Chemotherapy response b | |||
---|---|---|---|---|---|---|---|---|
Variables | Case No. (%) | HR (95% CI) | P Value | HR (95% CI) | P Value | OR (95% CI) | P Value | |
Age at surgery, y | Â | Â | Â | Â | Â | Â | Â | Â |
<50 | 25 (40.3) | 0.921 (0.439–1.932) | 0.828 | 0.763 (0.329–1.771) | 0.529 | 23 (40.3) | 1.094 (0.346–3.461) | 0.879 |
≥50 | 37 (59.4) | 1 |  | 1 |  | 35 (59.4) | 1 |  |
Histological subtypes | Â | Â | Â | Â | Â | Â | Â | Â |
Serous | 50 (80.6) | 1.493 (0.567–3.93) | 0.417 | 1.153 (0.390–3.412) | 0.796 | 46 (80.6) | 2.419 (0.47–12.454) | 0.291 |
Others | 12 (19.4) | 1 | Â | 1 | Â | 12 (19.4) | 1 | Â |
FIGO stage | Â | Â | Â | Â | Â | Â | Â | Â |
I-II | 18 (29.0) | 0.352 (0.123–1.012) | 0.053 | 0.143 (0.019–1.063) | 0.057 | 16 (29.0) | 0.257 (0.051–1.287) | 0.098 |
III-IV | 44 (71.0) | 1 | Â | 1 | Â | 42 (71.0) | 1 | Â |
Tumor categories | Â | Â | Â | Â | Â | Â | Â | Â |
Type I | 15 (24.2) | 0.647 (0.263–1.587) | 0.341 | 0.762 (0.281–2.071) | 0.595 | 15 (24.2) | 0.518 (0.126–2.136) | 0.363 |
Type II | 47 (75.8) | 1 | Â | 1 | Â | 43 (75.8) | 1 | Â |
Let-7e expression | Â | Â | Â | Â | Â | Â | Â | Â |
Low | 23 (37.1) | 3.204 (1.541–6.661) | 0.002 | 4.368 (1.804–10.575) | 0.001 | 21 (37.1) | 22.667 (5.114–100.457) | <0.0001 |
High | 39 (62.9) | 1 | Â | 1 | Â | 37 (62.9) | 1 | Â |
BRCA1 expression | Â | Â | Â | Â | Â | Â | Â | Â |
Low | 25 (40.3) | 1 | 0.078 | 1 | 0.350 | 23 (40.3) | 1 | 0.011 |
High | 37 (59.7) | 1.993 (0.925–4.294) |  | 1.510 (0.636–3.585) |  | 35 (59.7) | 7.875 (1.594–38.906) |  |
Rad51 expression | Â | Â | Â | Â | Â | Â | Â | Â |
Low | 32 (51.6) | 1 | 0.001 | 1 | 0.025 | 30 (51.6) | 1 | 0.001 |
High | 30 (48.4) | 3.584 (1.668–7.701) |  | 2.752 (1.133–6.682) |  | 28 (48.4) | 16.154 (3.212–81.252) |  |