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Table 2 Comparison of ovarian reserve and ovarian response parameters and IVF outcomes after DHEA supplementation(Mean ± SD)

From: The effect of dehydroepiandrosterone supplementation on ovarian response is associated with androgen receptor in diminished ovarian reserve women

Items

DHEA (n = 53)

group control group (n = 50)

P

Treatment variables

 T(ng/dl)

34.02 ± 19.02

25.58 ± 13.59

0.047b

 DHEAs(d2-3) (μg/dl)

16.52 ± 4.30

14.71 ± 4.26

0.019b

Ovarian reserve variables

 FSH(IU/L)

9.51 ± 1.78

10.16 ± 2.48

0.083b

 Inhibin B(d2-3)(pg/ml)

49.01 ± 15.56

45.53 ± 14.91

0.074b

 AMH(ng/ml)

0.96 ± 0.16

0.89 ± 0.20

0.058a

 AFC

5.34 ± 1.68

4.66 ± 1.44

0.085b

Ovarian response variables

 Total doses of Gn (IU)

2292.45 ± 842.27

2555.00 ± 963.94

0.151b

 Stimulation duration(days)

9.79 ± 1.71

10.18 ± 1.90

0.410b

 E2 on hCG day(pg/ml)

1903.28 ± 1178.43

1578.93 ± 956.63

0.339b

 Endometrial thickness on hCG day(mm)

9.73 ± 1.66

9.29 ± 2.11

0.245a

 N of retrieved oocytes

4.51 ± 2.40

3.70 ± 2.00

0.098b

 N of fertilization oocytes

3.75 ± 2.32

3.02 ± 1.95

0.084b

 N of embryos transferred

1.78 ± 0.49

1.88 ± 0.49

0.425b

 High quality embryos rate(%)

60.26(94/156)

58.27(74/127)

0.735c

Pregnancy outcomes

 Implantation rate of embryo(%)

23.08(15/65)

21.67(13/60)

0.850c

 Clinical pregnancy rate(%)

33.33(12/36)

28.13(9/32)

0.643c

 Early abortion rate(%)

0(0/12)

22.22(2/9)

0.171c

 Ectopic pregnancy rate(%)

0(0/12)

22.22(2/9)

0.171c

  1. aindependent samples t-tests, bMann-Whitney U test, c X 2 test