Fig. 6

TCF21 inhibits ovarian cancer cell invasion and miR-205 attenuates its inhibition of cell invasion (a) Photographs of invasive cells on Transwell membrane after transfection with TCF21 expression plasmid and 205-mimic. The experiments were performed at the same time with miR-205 inhibitor (Fig. 2c) and therefore, the same scrambled controls were used in the analysis of invasion. b Quantitative analysis of invasion viability. c Quantitative reverse-transcription PCR result showing MMP-2, MMP-7, MMP-9 and MMP-10 expression levels in ovarian cancer tissue and normal ovarian tissue. d Quantitative reverse-transcription PCR result showing MMP-2, MMP-7, MMP-9 and MMP-10 expression levels in OVCAR-5, OVCAR-8 and SKOV-3 cells after transfection with TCF21 expression plasmid and miR-205 mimic. Data presented as mean ± S.E, *P < 0.05 and **P < 0.01