Fig. 5From: WAP four-disulfide core domain protein 2 promotes metastasis of human ovarian cancer by regulation of metastasis-associated genesThe expression of ICAM-1,MMP2 and CD44 on WFDC2 and WFDC2 knockdown cells. a WFDC2,ICAM-1 and CD44 immunohistochemistry in WFDC2 knockdown and negative control xenografts; Xenograft tumor sections (HO8910) were stained with either anti-WFDC2 antibody,anti-CD44 antibody,anti-MMP2 or anti-ICAM-1 antibody. b, c, d, e.Normalized WFDC2,ICAM-1,MMP2and CD44 protein levels in WFDC2 knockdown and negtive control xenografts. *PÂ <Â 0.05 WFDC2 knockdown compared to negative control; f Summary of WFDC2-mediated molecular effects on ovarian cancer metastasisBack to article page