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Table 1 Cycles analysed in this study

From: Androstenedione response to recombinant human FSH is the most valid predictor of the number of selected follicles in polycystic ovarian syndrome: (a case-control study)

 

Group I

Group II

(Control Group)

(PCOS Group)

Age

29.8 ± 0.6

28.7 ± 0.6

Duration of infertility (years)

3.5 ± 0.3

3.4 ± 0.4

BMI (kg/m2)α

25 ± 0.7

27.7 ± 0.6

AMH(ng/mL)α

2.4 ± 0.2

9 ± 0.9

HOMAα

2.8 ± 0.4

3.8 ± 0.4

FSH (mIU/ml)α

7.2 ± 0.3

6.3 ± 0.2

LH (mIU/ml)α

6.5 ± 0.5

9.8 ± 0.6

TSH (μIU/mL)

2.7 ± 0.2

3.3 ± 0.7

PRL (ng/ml)

20.9 ± 1.2

22 ± 1.9

Initial Dose (IU/day)

70 ± 4.1

65 ± 3.7

Cycle Length (days)

12.2 ± 4.1

17 ± 0.6

Primary follicular/E2 response dayα

6.7 ± 0.4

9.4 ± 0.4

EM at trigger day (mm)

9.9 ± 0.3

9.4 ± 0.3

Maximum E2 (pg/dl)

453 ± 42.1

556.9 ± 89.3

Follicles >16 mm (n)

1.1 ± 0.1

1.4 ± 0.2

Follicles 12-16 mm (n)

1.2 ± 0.2

1.6 ± 0.3

Total number of follicles

1.9 ± 0.2

2.2 ± 0.3

P4 at trigger day (ng/mL)

0.7 ± 0.1

0.8 ± 0.1

Day 3 Total Testosterone (ng/mL)α

0.34 ± 0.28

0.87 ± 0.3

Primary androstenedione level (ng/mL)α

0.9 ± 0.1

1.4 ± 0.1

Primary androstenedione respond dayα

6.2 ± 0.3

7.4 ± 0.4

Time Lag (A4 → E2) initial responses (days)α

0.5 ± 0.4

2 ± 0.5

Maximum A4(ng/mL)α

1.8 ± 0.1

2.6 ± 0.3

Rise in A4 (%)α

66.5 ± 6.9

84.1 ± 7.4

A4 (AUC) (ng*days)α

3.6 ± 0.3

5.5 ± 1.3

A4 on the trigger day (ng/mL)α

1.3 ± 0.1

2.5 ± 0.4

  1. PCOS polycystic ovarian syndrome, AMH Anti-Müllerian hormone, HOMA homeostasis model for assesment of insulin resistance, FSH follicle-stimulating hormone, LH luteinising hormone, TSH thyroid-stimulating hormone, E 2 estradiol, PRL prolactin, EM endometrial thickness, P 4 progesterone, AUC area under the curve, A 4 androstenedione
  2. α P < 0.05