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Fig. 1 | Journal of Ovarian Research

Fig. 1

From: Suppressing miR-199a-3p by promoter methylation contributes to tumor aggressiveness and cisplatin resistance of ovarian cancer through promoting DDR1 expression

Fig. 1

A negative correlation between DDR1 and miR-199a-3p was observed in clinical ovarian cancer tissues. a The representative results of DDR1 expression in human ovarian cancer tissue compared to normal, by immunohistochemical analysis. b Kaplan–Meier survival curves for the ovarian cancer patients divided by the expression of DDR1. c Relative mRNA levels of DDR1 in ovarian cancer tissues compared with normal ovarian tissues. *P < 0.05. d Relative expression of miR-199a-3p in ovarian cancer tissues compared with normal ovarian tissues. *P < 0.05. e miR-199a-3p and DDR1 mRNA expression levels inversely correlated in 20 clinical samples. Statistical analysis to evaluate correlation was performed using Pearson’s correlation analysis (r = −0.5383, P = 0.0144)

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