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Table 2 Choriocarcinoma of the ovary: a summary of cases

From: A gestational choriocarcinoma of the ovary diagnosed by DNA polymorphic analysis: a case report and systematic review of the literature

Authors Age Reproductive history β-hCG (mIU/ml) Surgery Chemotherapy Outcome DNA polymorphic analysis
Gestational choriocacinoma
 Lorigan,1996 [24] 41 NS 151,500 TAH,BSO BEP then EI NED Yes
 Our case 27 G0 >200,000 ROC EP-EMA NED 32 mo Yes
Non-gestational choriocacinoma
 Vance,1985 [5] 9 NI 34 RO VEP NED 12 mo No
 Raju,1985 [6] 16 NI NS Autopsy None DOD No
 Axe,1985 [1] 6 NI Normal RO None NED 10 yrs No
 Axe,1985 [1] 11 NI Elevated RO MAV DOD No
 Sengupta, 1987 [7] 11 NI NS UO NS NS No
 Spingler,1990 [19] 20 Swyer syndrome NS Yes,NS NS DOD No
 Gribbon,1992 [8] NS NI Elevated Yes,NS NS DOD 4 mo No
 Gribbon,1992 [8] 11 NI Elevated Yes,NS NS NED 1 yr No
 Brown,1993 [9] 11 NI NS USO NS NED 32 mo No
 Trigueros,1995 [10] 21 NI 200,000 TAH,BSO PVB NED 4 yrs No
 Gungor,1999 [11] 16 NI 20,000 TAH, cytodeduction, omentectomy, appendectomy EMA-CO DOD 6 mo No
 Inaba,2000 [12] 12 NI 1,100,000 RSO,LOC, conservative debulking surgery BEP then EIC NED 12 mo No
 Goswami, 2001 [13] 18 NI 88,385 LSO,ROC,omental and peritoneal biopsies MA and oral chlorambucil NED 5 mo No
 Ozdemir, 2002 [14] 13 NI 91,028 RSO MAC NED 9 mo No
 Tsujioka, 2003 [20] 19 NS 110,000 LSO EMA-CO NS Yes
 Koo,2006 [21] 33 G0 185,000 TAH,BSO,PLND MAC NED 18 mo Yes
 Yamamoto,2007 [22] 19 NS 206,949 LO EMA,then EA NED 12 mo Yes
 Kong,2009 [4] 10 NI NS LSO,partial omentectomy PVB NED 3 mo No
 Exman,2013 [23] 24 G1P0 675,713 TAH,BSO BEP NED Yes
 Heo,2014 [15] 12 NI 20,257 LSO BEP NED 14 mo No
 Hayashi,2015 [16] 10 NI 6600 RSO BEP NED 62 mo No
 Xin,2015 [17] 23 NI 18,000 tumor enucleation, LSO, pelvic peritonectomy, PaLND, omentectomy BEP NED 9 mo No
 Wang,2016 [18] 13 NI Elevated TAH,LSO,debulking surgery PVB DOD 3 mo No
 Wang,2016 [18] 13 NI NS LSO NS Lost follow-up in 1 yr No
Uncertain etiology
 Jacobs,1982 [33] 30 G1P1 350,000 lumpectomy MTX NED 2 yrs No
 Axe,1985 [1] 21 G1P1 Elevated RO MAV NED 8 yrs No
 Axe,1985 [1] 20 NS Elevated RO,appendectomy MTX NED 16 yrs No
 Axe,1985 [1] 36 G4P2 Elevated TAH,BSO,appendectomy MTX NED 19 yrs No
 Axe,1985 [1] 35 G4P4 Elevated TAH,BSO,PLND PBC NED 9 mo No
 Kim,1990 [35] 16 G0 565,000 TAH,BSO MAC DOD during chemo unknown
 Shin,1994 [36] 45 G6P3 132,005 TAH,BSO MAC NED 1 yr unknown
 Byeun,1995 [37] 28 G3P2 13,378 RSO EMA NED 1 yr unknown
 Balat,2004 [38] 28 NS 13,378 TAH,BSO,PLND BEP DOD during chemo No
 Bazot,2004 [39] 38 P0 2,460,000 TAH,BSO NS NED 7 yrs No
 Gerson,2005 [25] 33 G5P3 564,000 RSO,TAH,LSO,splenectomy EMA-CO NED 12 mo No
 Corakci,2005 [34] 22 G1P1 15,050 TAH,BSO,PLND,PaLND BEP NED 25 mo No
 Hirabayashi,2006 [40] 50 G0 704 TAH,RSO,PLND P(ip) + TC,EP-EMA,P-EMA(ip) DOD 10 mo No
 Roghaei,2007[41] 47 G5P5, menopause 970 TAH,BSO,PLND EMA-CO NED No
 Park,2009 [26] 55 G5P3 64,838 TAH,BSO BEP NED 20 mo No
 Mood,2009 [42] 31 G9P1 >1000 RSO EMA-CE NED 7 yrs No
 Mood,2009 [42] 32 G3P2 5500 TAH, BSO, debulking surgery and omentectomy BEP to EMA-CE NED 5 yrs No
 Gon,2010 [43] 21 G0 279,000 RSO NS NS No
 Lv,2011 [2] 48 G1P1 7664 sub-extensive TAH,BSO,PLND,PaLND BEP NED 12 mo No
 Choi,2013 [27] 33 G4P2 74,612 LO,ROC EMA NED 5 yrs No
 Haruma,2015 [44] 19 G0 373,170 LSO EMA-CO NED 10 mo No
 Rao,2015 [45] 26 G1P1 8160 RSO,partial omentectomy, partial splenectomy and right adrenalectomy BEO brain metastasis 2 years after primary treatment No
  1. NS not stated, NI no intercourse, NED no evidence of disease, DOD dead of disease, mo, months, yr. year