Fig. 2

Couples exhibiting LCLCG and HCLCG in different zones of pesticide exposure. LCLCG: Low Centrally Located Cytoplasmic Granulation (CLCG) in a group of couples with oocytes exhibiting a low prevalence of CLCG of under 25%; HCLCG: High CLCG in a group of couples with oocytes exhibiting a high prevalence of CLCG of over 75%. The map of the Picardy region of France for pesticide studies was created in 2009 by GREPP (the Picardy regional group for pesticide studies. The pesticide exposure estimation in each zone was calculated in g/ha in the surface water mass used in the agricultural area. The main zone of low pesticide exposure included zones 1 and 2,and zones 3 and 4 represented the main zone of high pesticide exposure. A difference was considered significant when stage < 0.05; (ns): not significant. Four zones of pesticide use: - Zone 1: 0 to 2000 g/ha (n: 13 areas) – 28 women lived in this zone. - Zone 2: 2000 to 3000 g/ha (n: 29) – 55 women lived in this zone. - Zone 3: 3000 to 4000 g/ha (n: 25) – 32 women lived in this zone. - Zone 4: 4000 to 5000 g/ha (n: 21) – 36 women lived in this zone