Skip to main content

Table 2 ICSI outcomes in couples compared to CLCG prevalence

From: Impact of oocytes with CLCG on ICSI outcomes and their potential relation to pesticide exposure

 

LCLCG

(n = 83)

HCLCG

(n = 68)

p-value

Total number of oocytes

1178

943

-

Oocytes per patient

14.1 ± 5.7

13.6 ± 5.5

ns

MII per patient

10.4 ± 4.1

9.4 ± 4.2

ns

Maturation rate (%)

(868/1178)

74%

(653/943)

69%

ns

Embryological outcomes

Fertilization rate (%)

(577/868)

66%

(388/653)

59%

ns

Cleavage rate (%)

(576/577)

99%

(321/388)

82%

0.04 (s)

Best embryo quality (A + B) rate (%)

(358/576)

62%

(200/321)

62%

ns

Embryo cryopreservation rate (%)

(150/423)

35%

(78/211)

37%

ns

Cryopreserved embryos per patient

1.8 ± 0.5

1.2 ± 0.7

0.01 (s)

Total number oftransferredembryos

153

110

-

Transferred embryos per patient

1.9 ± 0.8

1.6 ± 1

ns

Total embryo transfer cycles

79

55

-

Clinical outcomes

Clinical pregnancy rate (%)

(28/79)

35%

(15/55)

27%

ns

Early miscarriage rate (%)

(3/28)

11%

(7/15)

47%

0.01 (s)

Ongoing pregnancy rate (%)

(25/79)

32%

(8/55)

14%

0.01 (s)

Late miscarriage rate (%)

(1/25)

4%

(1/8)

12%

0.02 (s)

Live birth rate (%)

(24/79)

30%

(7/55)

13%

0.01 (s)

  1. Results are expressed as n(%) or mean (M) ± standard deviation (SD). A difference was considered significant (s) when P < 0.05; (ns), not significant
  2. LCLCG Low Centrally Located Cytoplasmic Granulation (CLCG)in a group of couples with oocytes exhibiting a low prevalence of CLCG of under 25%, HCLCG High CLCG in a group of couples with oocytes exhibiting a high prevalence of CLCG of over 75%, MII Metaphase II