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Table 2 ICSI outcomes in couples compared to CLCG prevalence

From: Impact of oocytes with CLCG on ICSI outcomes and their potential relation to pesticide exposure

  LCLCG
(n = 83)
HCLCG
(n = 68)
p-value
Total number of oocytes 1178 943 -
Oocytes per patient 14.1 ± 5.7 13.6 ± 5.5 ns
MII per patient 10.4 ± 4.1 9.4 ± 4.2 ns
Maturation rate (%) (868/1178)
74%
(653/943)
69%
ns
Embryological outcomes Fertilization rate (%) (577/868)
66%
(388/653)
59%
ns
Cleavage rate (%) (576/577)
99%
(321/388)
82%
0.04 (s)
Best embryo quality (A + B) rate (%) (358/576)
62%
(200/321)
62%
ns
Embryo cryopreservation rate (%) (150/423)
35%
(78/211)
37%
ns
Cryopreserved embryos per patient 1.8 ± 0.5 1.2 ± 0.7 0.01 (s)
Total number oftransferredembryos 153 110 -
Transferred embryos per patient 1.9 ± 0.8 1.6 ± 1 ns
Total embryo transfer cycles 79 55 -
Clinical outcomes Clinical pregnancy rate (%) (28/79)
35%
(15/55)
27%
ns
Early miscarriage rate (%) (3/28)
11%
(7/15)
47%
0.01 (s)
Ongoing pregnancy rate (%) (25/79)
32%
(8/55)
14%
0.01 (s)
Late miscarriage rate (%) (1/25)
4%
(1/8)
12%
0.02 (s)
Live birth rate (%) (24/79)
30%
(7/55)
13%
0.01 (s)
  1. Results are expressed as n(%) or mean (M) ± standard deviation (SD). A difference was considered significant (s) when P < 0.05; (ns), not significant
  2. LCLCG Low Centrally Located Cytoplasmic Granulation (CLCG)in a group of couples with oocytes exhibiting a low prevalence of CLCG of under 25%, HCLCG High CLCG in a group of couples with oocytes exhibiting a high prevalence of CLCG of over 75%, MII Metaphase II