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Table 2 ICSI outcomes in couples compared to CLCG prevalence

From: Impact of oocytes with CLCG on ICSI outcomes and their potential relation to pesticide exposure

  LCLCG (n = 83) HCLCG (n = 68) p-value
Total number of oocytes 1178 943 -
Oocytes per patient 14.1 ± 5.7 13.6 ± 5.5 ns
MII per patient 10.4 ± 4.1 9.4 ± 4.2 ns
Maturation rate (%) (868/1178) 74% (653/943) 69% ns
Embryological outcomes Fertilization rate (%) (577/868) 66% (388/653) 59% ns
Cleavage rate (%) (576/577) 99% (321/388) 82% 0.04 (s)
Best embryo quality (A + B) rate (%) (358/576) 62% (200/321) 62% ns
Embryo cryopreservation rate (%) (150/423) 35% (78/211) 37% ns
Cryopreserved embryos per patient 1.8 ± 0.5 1.2 ± 0.7 0.01 (s)
Total number oftransferredembryos 153 110 -
Transferred embryos per patient 1.9 ± 0.8 1.6 ± 1 ns
Total embryo transfer cycles 79 55 -
Clinical outcomes Clinical pregnancy rate (%) (28/79) 35% (15/55) 27% ns
Early miscarriage rate (%) (3/28) 11% (7/15) 47% 0.01 (s)
Ongoing pregnancy rate (%) (25/79) 32% (8/55) 14% 0.01 (s)
Late miscarriage rate (%) (1/25) 4% (1/8) 12% 0.02 (s)
Live birth rate (%) (24/79) 30% (7/55) 13% 0.01 (s)
  1. Results are expressed as n(%) or mean (M) ± standard deviation (SD). A difference was considered significant (s) when P < 0.05; (ns), not significant
  2. LCLCG Low Centrally Located Cytoplasmic Granulation (CLCG)in a group of couples with oocytes exhibiting a low prevalence of CLCG of under 25%, HCLCG High CLCG in a group of couples with oocytes exhibiting a high prevalence of CLCG of over 75%, MII Metaphase II