Epithelial ovarian cancer | Diagnostic criteria (%) | MMP-7 | TIMP-1 | HE4 | CA125 |
---|---|---|---|---|---|
Stage I | SE | 42 | 4 | 54 | 35 |
SP | 95 | 95 | 95 | 98 | |
PPV | 78 | 25 | 81 | 90 | |
NPV | 83 | 73 | 80 | 75 | |
Stage II | SE | 46 | 23 | 54 | 38 |
SP | 95 | 95 | 95 | 98 | |
PPV | 78 | 67 | 82 | 90 | |
NPV | 81 | 76 | 71 | 82 | |
Stage III | SE | 77 | 35 | 75 | 77 |
SP | 95 | 95 | 95 | 98 | |
PPV | 87 | 75 | 88 | 95 | |
NPV | 92 | 78 | 86 | 90 | |
Stage IV | SE | 79 | 16 | 88 | 83 |
SP | 95 | 95 | 95 | 98 | |
PPV | 86 | 80 | 86 | 95 | |
NPV | 93 | 76 | 90 | 92 | |
Total group | SE | 61 | 20 | 68 | 58 |
SP | 95 | 95 | 95 | 98 | |
PPV | 93 | 87 | 96 | 98 | |
NPV | 61 | 44 | 66 | 60 |