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Table 3 The diagnostic criteria of MMP-7, TIMP-1, HE4 and CA 125 in epithelial ovarian cancer patients

From: Plasma levels of MMP-7 and TIMP-1 in laboratory diagnostics and differentiation of selected histological types of epithelial ovarian cancers

Epithelial ovarian cancer Diagnostic criteria (%) MMP-7 TIMP-1 HE4 CA125
Stage I SE 42 4 54 35
SP 95 95 95 98
PPV 78 25 81 90
NPV 83 73 80 75
Stage II SE 46 23 54 38
SP 95 95 95 98
PPV 78 67 82 90
NPV 81 76 71 82
Stage III SE 77 35 75 77
SP 95 95 95 98
PPV 87 75 88 95
NPV 92 78 86 90
Stage IV SE 79 16 88 83
SP 95 95 95 98
PPV 86 80 86 95
NPV 93 76 90 92
Total group SE 61 20 68 58
SP 95 95 95 98
PPV 93 87 96 98
NPV 61 44 66 60