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Table 3 The diagnostic criteria of MMP-7, TIMP-1, HE4 and CA 125 in epithelial ovarian cancer patients

From: Plasma levels of MMP-7 and TIMP-1 in laboratory diagnostics and differentiation of selected histological types of epithelial ovarian cancers

Epithelial ovarian cancer

Diagnostic criteria (%)

MMP-7

TIMP-1

HE4

CA125

Stage I

SE

42

4

54

35

SP

95

95

95

98

PPV

78

25

81

90

NPV

83

73

80

75

Stage II

SE

46

23

54

38

SP

95

95

95

98

PPV

78

67

82

90

NPV

81

76

71

82

Stage III

SE

77

35

75

77

SP

95

95

95

98

PPV

87

75

88

95

NPV

92

78

86

90

Stage IV

SE

79

16

88

83

SP

95

95

95

98

PPV

86

80

86

95

NPV

93

76

90

92

Total group

SE

61

20

68

58

SP

95

95

95

98

PPV

93

87

96

98

NPV

61

44

66

60