Skip to main content

Table 2 Univariate and multivariate analyses of risk factors for ovarian metastasis in patients with cervical adenocarcinoma

From: Ovarian preservation in adenocarcinoma of the uterine cervix

Parameter N (%) Univariate analyses    Multivariate analyses
Total no. of patients enrolled 312 Ovarian metastasis Odds ratio p-value
   Yes No p-value   
Age at surgery       
  < 60 282 (90.4) 12 270 0.544   
  ≥ 60 30 (9.6) 2 28   
FIGO stage       
 I 226 (72.4) 5 221 0.002* 2.445 0.243
 II 86 (27.6) 9 77
Tumor diameter (cm)       
  < 4 221 (70.8) 7 214 0.079   
  ≥ 4 91 (29.2) 7 84   
Differentiation       
 G1 + G2 191 (61.2) 8 182 0.756   
 G3 121 (38.8) 6 115   
Tumour morphology       
 Exophytic 109 (34.9) 8 101 0.075   
 Endophytic 203 (65.1) 6 197   
Deep stromal invasion       
 Superficial (<2/3) 210 (67.3) 4 206 0.002* 1.307 0.743
 Deep (≥2/3) 102 (32.7) 10 92
Parametrial invasion       
 Negative 296 (94.9) 8 288 5.80E-11* 14.125 0.005*
 Positive 16 (5.1) 6 10
Lymph-vascular space invasion       
 Negative 197 (63.1) 7 190 0.297   
 Positive 115 (36.9) 7 108   
Pelvic node status       
 Negative 227 (72.8) 10 217 0.909   
 Positive 85 (27.2) 4 81   
Fallopian tube invasion       
 Negative 302 (96.8) 10 292 3.51E-8* 1.837 0.338
 Positive 10 (3.2) 4 6
Para-aortic node status       
 Negative 305 (97.8) 13 292 0.205   
 Positive 7 (2.2) 1 6   
Infiltration to vagina       
 Yes 58 (18.6) 8 50 1.48E-4* 4.167 0.047*
 No 254 (81.4) 6 248
Endometrial invasion       
 Negative 300 (96.2) 11 289 4.65E-4* 3.156 0.213
 Positive 12 (3.8) 3 9
Uterine corpus invasion       
 Negative 252 (80.8) 5 247 1.20E-5* 5.178 0.019*
 Positive 60 (19.2) 9 51
Perineural invasion       
 Negative 271 (86.9) 9 262 0.011* 0.273 0.174
 Positive 41 (13.1) 5 36
  1. FIGO The International Federation of Gynecology and Obstetrics
  2. * p < 0.05