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Table 1 Results from meta-analysis studies providing clinical insights on the effect of endometriosis disease on oocyte quality.

From: Is the oocyte quality affected by endometriosis? A review of the literature

First author, Year [Ref]

Endometriosis groupsa

Outcome: MII oocytes retrieved

Outcome: Fertilization rate

Studies included (n)

Endometriosis vs controls (95% CI)

Studies included (n)

Endometriosis vs controls (95% CI)

Barnhart, 2002 [56]

Overall

Stage I-II

Stage III-IV

  

Unknown

Unknown

Unknown

OR 0.81 (0.79 to 0.83)c

OR 0.94 (0.93 to 0.96)c

OR 1.54 (1.39 to 1.70)c

Harb, 2013 [57]

Untreated Stage I-II

Untreated Stage III-IV

  

7

3

RR 0.93 (0.87 to 0.99)c

RR 1.01 (0.93 to 1.10)

Yang, 2015 [58]

Untreated endometrioma

2

MD −3.61 (−4.44 to −2.78)c

2

OR 1.06 (0.71 to 1.60)b

Rossi, 2016 [59]

Overall

Stage I-II

Stage III-IV

Treated disease (surgery)

Untreated disease

Endometrioma

4

2

3

3

1

2

OR −1.22 (−2.38 to −0.06)c

OR −0.55 (−1.34 to 0.25)

OR −0.83 (−1.73 to 0.08)

OR −1.62 (−3.31 to 0.07)

OR −0.50 (−1.59 to 0.59)

OR −2.48 (−4.43 to −0.53) c

  
  1. MD mean difference, OR odds ratio, RR relative risk
  2. aWhere not specified, history of treatment vs untreated disease is unknown
  3. bControl group: contralateral healthy ovary
  4. cStatistically significant