Skip to main content

Table 1 Results from meta-analysis studies providing clinical insights on the effect of endometriosis disease on oocyte quality.

From: Is the oocyte quality affected by endometriosis? A review of the literature

First author, Year [Ref] Endometriosis groupsa Outcome: MII oocytes retrieved Outcome: Fertilization rate
Studies included (n) Endometriosis vs controls (95% CI) Studies included (n) Endometriosis vs controls (95% CI)
Barnhart, 2002 [56] Overall
Stage I-II
Stage III-IV
   Unknown
Unknown
Unknown
OR 0.81 (0.79 to 0.83)c
OR 0.94 (0.93 to 0.96)c
OR 1.54 (1.39 to 1.70)c
Harb, 2013 [57] Untreated Stage I-II
Untreated Stage III-IV
   7
3
RR 0.93 (0.87 to 0.99)c
RR 1.01 (0.93 to 1.10)
Yang, 2015 [58] Untreated endometrioma 2 MD −3.61 (−4.44 to −2.78)c 2 OR 1.06 (0.71 to 1.60)b
Rossi, 2016 [59] Overall
Stage I-II
Stage III-IV
Treated disease (surgery)
Untreated disease
Endometrioma
4
2
3
3
1
2
OR −1.22 (−2.38 to −0.06)c
OR −0.55 (−1.34 to 0.25)
OR −0.83 (−1.73 to 0.08)
OR −1.62 (−3.31 to 0.07)
OR −0.50 (−1.59 to 0.59)
OR −2.48 (−4.43 to −0.53) c
  
  1. MD mean difference, OR odds ratio, RR relative risk
  2. aWhere not specified, history of treatment vs untreated disease is unknown
  3. bControl group: contralateral healthy ovary
  4. cStatistically significant