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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: R-spondin2, a novel target of NOBOX: identification of variants in a cohort of women with primary ovarian insufficiency

Fig. 2

Schematic representation of RSPO2 gene and RSPO2 protein. a R-spondin2 gene contains 6 exons (reference sequence was based on NC_000008.11 and ENSG00000147655). Locations of 9 variations are indicated by an arrow. b R-spondin2 mRNA includes exons 2 to 6 encoding the protein (reference sequence was based on NM_178565 and ENST00000276659). c RSPO2 encompasses a signal peptide (SP), two cysteine-rich furin like repeats (FL) and a thrombospondin type 1 repeat domain (TR) (reference sequence was based on NP_848660)

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