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Table 2 Clinical and hormonal characteristics of 100 POI patients

From: R-spondin2, a novel target of NOBOX: identification of variants in a cohort of women with primary ovarian insufficiency

Population studied

Hormonal evaluation at diagnosis

Amenorrhea

n

Median age at diagnosis (range)

FSH [SD]

(range) (IU/L)

LH [SD]

(range) (IU/L)

Estradiol [SD]

(range) (pmol/L)[

Inhibin B [SD]

(range) (ng/L)

AMH [SD]

(range) (pmol/L)

Primary

20

18 years (13–32)

70.0 [33]

(20–164)

35.1 [18.7]

(9–100)

52.8 [60.5]

(0–234)

14 [9.5]

(0–42)

1.3 [2.0]

(0–11)

Secondary

80

29 years (15–39)

Normal range of basal levels in controls

(3–9)

(1–5)

(73–1284)

(60–200)

(15.7–48.5)