Fig. 9

Effects of p53 knockdown on the expressions of G2/M related signaling proteins and proliferation and apoptosis related proteins measured by western blot (B: Blank, NC: Negative Control, K: Knockdown). Knockdown of p53 in ovarian cancer cells could decrease the activities of p53-CDK1 signaling pathway, and affect the expressions of its downstream proliferation and apoptosis related proteins. Histogram graphs show relative values of protein expression in each group cells measured by western blot. Each bar represents the mean ± SD.* P < 0.05