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Table 1 Mean ± SEM of body weight, glucose level, body mass index, body mass gain, ovarian diameter, abdominal and thoracic circumference in control, PCOS, metformin, GAB 1 (100 mg/kg) and GABA 2 (500 mg/kg) treated groups before and after 36 days of experiment

From: Protective effects of GABA against metabolic and reproductive disturbances in letrozole induced polycystic ovarian syndrome in rats

Parameters Control PCOS Metformin GABA1 GABA2
Initial Body Weight (gm) 156 ± 01.37 156 ± 05.38 157 ± 07.57 150 ± 05.79 157 ± 04.22
Final Body Weight (gm) 181 ± 04.11 260 ± 02.81*** 203 ± 03.29+ 210 ± 04.57**++ 222.2 ± 02.15**++
Initial Glucose (mg/dL) 117.20 ± 01.93 103.20 ± 02.81 122.41 ± 03.29 113.00 ± 04.57 120.40 ± 02.15
Final Glucose (mg/dL) 120.22 ± 03.21 166.46 ± 20.00*** 135.21 ± 01.91++ 129.00 ± 05.08+ 138.40 ± 06.20+
Body mass Index (g/cm2) 0.49 ± 0.01 0.54 ± 0.02 0.47 ± 0.01 0.72 ± 0.03 0.69 ± 0.04
Body mass gain (g/kg) 4.34 ± 0.94 27.76 ± 8.61 16.21 ± 5.04 29.66 ± 6.47 15.17 ± 7.21
Right Ovary diameter (mm) 4.80 ± 00.37 5.10 ± 01.04 4.60 ± 00.25 6.10 ± 00.96 5.80 ± 00.12
Left Ovary diameter (mm) 5.00 ± 0.44 5.60 ± 0.24 5.20 ± 0.20 6.00 ± 0.15 5.70 ± 0.20
Abdominal Circumference (cm) 1.06 ± 0.09 1.05 ± 0.31 1.06 ± 0.51 1.04 ± 0.44 1.09 ± 0.34
Thoracic circumference (cm) 1.06 ± 0.23 1.05 ± 0.10 1.06 ± 0.18 1.16 ± 0.29 1.22 ± 0.24
  1. Values are expressed as Mean ± SEM
  2. *, **, *** indicate significance from the control group at P < 0.001, 0. 01 and 0.05 probability level
  3. +, ++, +++ indicate significance from the PCOS group at P < 0.001, 0. 01 and 0.05 probability level