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Table 1 Clinical and morphological characteristics of EOC patients with or without EM

From: Endometriosis is the independent prognostic factor for survival in Chinese patients with epithelial ovarian carcinoma

 

NON-EAOC

EAOC

P

Numbers

236

68

 

Age(year)(median[IQR])

52.0 [44.00,62.00]

45.00 [40.00,49.50]

<0.001a

 Menopause

  

<.0001a

  Pre-

108 (45.96%)

53 (76.81%)

 

  Post-

127 (54.04%)

16 (23.19%)

 

 Gravid

  

0.6506

  0

26 (11.06%)

9 (13.04%)

 

   > =1

209 (88.94%)

60 (86.96%)

 

 Parity

  

0.5637

  0

41 (17.45%)

10 (14.49%)

 

   > =1

194 (82.55%)

59 (85.51%)

 

 Symptoms

   

  Abdominal pain

  

0.3989

  Yes

76 (32.34%)

17 (24.64%)

 

  No

158 (67.23%)

52 (75.36%)

 

 Bloating

  

0.0193a

  Yes

54 (22.98%)

7 (10.14%)

 

  No

181 (77.02%)

62 (89.86%)

 

 Palpable mass

  

0.2629

  Yes

59 (25.11%)

22 (31.88%)

 

  No

176 (74.89%)

47 (68.12%)

 

 Incidental finding

  

0.1232

  Yes

33 (14.04%)

15 (21.74%)

 

  No

202 (85.96%)

54 (78.26%)

 

 Irregular menstruation

  

0.1111

  Yes

19 (8.09%)

10 (14.49%)

 

  No

216 (91.91%)

59 (85.51%)

 

 Postmenopausal bleeding

  

0.0610

  Yes

18 (7.66%)

1 (1.45%)

 

  No

217 (92.34%)

68 (98.55%)

 

 Cachexia

  

0.0814

  Yes

10 (4.26%)

0 (0%)

 

  No

225 (95.74%)

69 (100%)

 

 Abnormal vaginal discharge

  

0.4420

  Yes

2 (0.85%)

0 (0%)

 

  No

233 (99.15%)

69 (100%)

 

Pre-surgery Ca125 (IU/ml) (median[IQR])

256.20 [62.96, 959.30]

89.50 [37.80, 346.85]

<0.001a

 Ca125 in normal range

  

0.2110

  Yes

39 (16.6%)

16 (23.19%)

 

  No

196 (83.4%)

53 (76.81%)

 

Tumor size (cm) (median[IQR])

9.00 [6.00,13.00]

10.00 [7.00,15.000]

0.245

 Side of ovarian tumor

  

0.3904

  Unilateral

161 (68.51%)

51 (73.91%)

 

  Bilateral

74 (31.49%)

18 (26.09%)

 

 Breast cancer history

  

0.1204

  Yes

8 (3.4%)

0 (0%)

 

  No

227 (96.6%)

69 (100%)

 

 HT history

  

0.2433

  Yes

45 (19.15%)

9 (13.04%)

 

  No

190 (80.85%)

60 (86.96%)

 

 DM history

  

0.2263

  Yes

16 (6.81%)

2 (2.9%)

 

  No

219 (93.19%)

67 (97.1%)

 

 Hysterectomy history

  

0.1469

  Yes

7 (2.98%)

0 (0%)

 

  No

228 (97.02%)

69 (100%)

 

 Tube ligation history

  

0.0379a

  Yes

14 (5.96%)

0 (0%)

 

  No

221 (94.04%)

69 (100%)

 
  1. Abbreviation: EOC, epithelial ovarian carcinoma; EM, endometriosis; EAOC, endometriosis-associated ovarian cancer; IQR, InterQuartile Range; Ca125, cancer antigen 125; HT, hypertension; DM, diabetic mellitus;
  2. athe difference reached statistical significance