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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: Food restriction during pregnancy and female offspring fertility: adverse effects of reprogrammed reproductive lifespan

Fig. 4

Hematoxylin and eosin staining of paraffinized ovarian sections from FR1 and FR2 females showing the generation of MNOFs. a Primordial follicle with two nuclei- oocyte. b Secondary follicle containing one oocyte with two proportional nuclei (c) Secondary follicle containing one merged oocyte with four disproportional nuclei. d Secondary follicle with two oocytes that are very close to each other, suggesting that they will probably fuse soon to form a heterokaryon. e Secondary follicle containing two semi-fused oocytes (arrowhead). f The same secondary follicle in (e) but at another level of section. Scale bar = 200 μm

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