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Table 1 Concentrations of TIMP3, MMP3, HE4 and CA125 in blood serum, depending on the histopathologic diagnosis of patients

From: Suitability assessment of baseline concentration of MMP3, TIMP3, HE4 and CA125 in the serum of patients with ovarian cancer

variable ovarian cancer ovarian simple cysts p
n mean
range
median
95% CI
n mean
range
median
95% CI
age 44 61.4
(49–78)
62.2
(52–76.4)
30 58
(42–66)
58.6
(44–62.5)
NS
TIMP3 [pg/ml] 44 138
(67–198)
143
(151–188)
30 285
(148–368)
291
(298–355)
p = 0.001
MMP3
[pg/ml]
44 20836
(16211–28994)
21022
(16750–26877)
30 14657
(10987–21003)
15221
(11234–15001)
p = 0.0002
HE4
[pmol/l]
44 423
(238–698)
451.6
(250.2–644)
30 54.6
(41–79.6)
57
(44–75.2)
p = 0.0004
CA125
[U/ml]
44 728
(432–1254)
790.3
(478.1–1187)
30 19.3
(11.3–37.1)
25
(14.3–35.2)
p = 0.0001
variable ovarian cancer endometrial ovarian cysts p
n mean
range
median
95% CI
n mean
range
median
95% CI
age 44 61.4
(49–78)
62.2
(52–76.4)
30 48.9
(40.2–64.3)
48
(46–64)
NS
TIMP3 [pg/ml] 44 138
(67–198)
143
(151–188)
30 223
(143–276)
241
(256–270)
p = 0.003
MMP3
[pg/ml]
44 20836
(16211–28994)
21022
(16750–26877)
30 14111
(10198–19872)
15231
(11263–18862)
p = 0.004
HE4
[pmol/l]
44 423
(238–698)
451.6
(250.2–644)
30 61.3
(34–87)
64
(37.6–82.4)
p = 0.002
CA125
[U/ml]
44 728
(432–1254)
790.3
(478.1–1187)
30 45.2
(23–98)
47
(24.5–86.2)
p = 0.001