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Table 4 Individual proteins concentration levels in patients with ovarian cancer, depending on the staging and grading

From: Suitability assessment of baseline concentration of MMP3, TIMP3, HE4 and CA125 in the serum of patients with ovarian cancer

  

Ascites/

No Ascites

Optimal debulking/neoadjuvant chemotherapy

Low grade/high grade

FIGO I, II/

FIGO III, IV

MMP3 [pgl/ml]

mean

23345/18998

16034/25620

17423/20028

23698/16542

median

24121/29435

17265/28672

17689/21106

24340/17863

p

NS

0.005

NS

0.004

TIMP3 [pg/ml]

mean

131/203

126/198

204/159

185/122

median

139/212

129/202

220/161

198/109

p

0.001

0.002

0.03

0

HE4

[pmol/l]

mean

765/542.2

568.3/683.4

180.4/560.3

407/211

median

771/551

591.4/712.4

198.2/436.3

418/243

p

NS

NS

0.001

0.002

CA125

[U/ml]

mean

1987.2/923.8

672.2/1231

569.2/608.8

2789/1786

median

2012.4/986.5

689.1/1308

583/703.2

2853/1911

p

0.0003

0.01

NS

0.0037