Fig. 3
From: DHEA-induced ovarian hyperfibrosis is mediated by TGF-β signaling pathway
Expression of TGF-β downstream signaling molecules. a-b Levels of ovarian CTGF and fibronectin proteins (left) and mRNA (middle), detected by western blotting and quantitative-PCR assay. c mRNA levels of MMP2/MMP9 in Oil + DHEA-induced rats compared with Oil-treated rats. a-SMA is highly expressed in DHEA-induced rats. Oil + DHEA-induced rat ovaries (e) show a signally proliferation of a-SMA compared with Oil-treated rat ovaries (d). ×100. Ovarian protein was harvested to measure a-SMA expression (f). n = 6 in each group. Data are mean ± S.D.; *p ≤ 0.05