Table 1 Literature review of struma ovarii with pseudo-Meigs’ syndrome and elevated CA125 levels
Study | Age (y) Gravidity | Size (cm) | CA125 (U/ml) | Preoperative thyroid function | Imaging modalities | Preoperative diagnosis | Intraoperative diagnosis by frozen section | Treatment |
|---|---|---|---|---|---|---|---|---|
Bethune et al. 1966 [1] | 62 multipara | 9 × 5 × 5 | 1621 | WNL | X-ray, US, CT | Suspected ovarian malignancy | N/A | ATH + BSO + infracolic OM |
Long et al. 2001 [9] | 53 multipara | 15 × 11 × 7 | 540 | N/A | X-ray, US, CT | Suspected ovarian malignancy | Struma ovarii | ATH + BSO + infracolic OM |
78 multipara | 12.2 × 10 × 5.2 | 124.9 | N/A | X-ray, US, CT | Suspected ovarian malignancy | Multilocular cysts lined by columnar epithelium | ATH + BSO | |
Huh et al. 2002 [10] | 65 multipara | 5 × 4 × 4 | 402 | Hypothyroidism | US, CT | Suspected ovarian malignancy | Struma ovarii | ATH + BSO + appendectomy + omental biopsy |
Loizzi et al. 2005 [11] | 65 multipara | 7 × 7 | 161 | Hyperthyroidism | X-ray, CT | Suspected ovarian malignancy | Struma ovarii | RSO |
Uehara and Sawada 2007 [12] | 67 N/A | About 7 | 2086 | WNL | CT | Struma ovarii with Meigs’ syndrome although the ovarian tumor mimicked an advanced malignancy | N/A | ATH + BSO |
Obeidat and Amarin 2007 [13] | 52 multipara | 10 × 15 × 8 | 149 | N/A | X-ray, US | Suspected ovarian malignancy | N/A | ATH + BSO + OM |
Mitrou et al. 2008 [14] | 55 N/A | 22 × 23 × 10 | 3803 | N/A | CT | Suspected ovarian malignancy | N/A | ATH + BSO + infracolic OM + lymph node sampling |
Rana et al. 2009 [15] | 70 N/A | 7.5 × 5.5 × 4 | 284 | WNL | X-ray, US, CT | Suspected ovarian malignancy | N/A | ATH + BSO + partial OM |
Jiang et al. 2010 [16] | 46 multipara | 20 × 18 × 15 | 1230.9 | N/A | CT | Suspected ovarian malignancy | Struma ovarii | ATH + BSO |
Obeidat and Saida 2012 [17] | 55 multipara | 21 × 21 × 9 | 872 | N/A | US, CT, MRI | Suspected ovarian malignancy | N/A | Neoadjuvant chemotherapy (carboplatin and paclitaxel) followed by laparoscopic LSO for obesity |
Mostaghel et al. 2012 [18] | 72 multipara | 9 | 607.4 | N/A | X-ray, US, CT | Suspected ovarian malignancy | Granulosa cell tumor | ATH + BSO + OM |
Jin et al. 2015 [19] | 52 multipara | 7 × 5 | 1289 | N/A | US, CT | Suspected ovarian malignancy | Cystic mature teratoma with a large component of thyroid | ATH + BSO |
Present | 50 multipara | 10 × 8 × 7 | 1237 | WNL | X-ray, US, CT, MRI, FDG PET, 123I scintigraphy | Highly suggestive of struma ovarii with pseudo-Meigs’ syndrome | Struma ovarii | ATH + BSO |