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Table 1 Literature review of struma ovarii with pseudo-Meigs’ syndrome and elevated CA125 levels

From: Precise preoperative diagnosis of struma ovarii with pseudo-Meigs’ syndrome mimicking ovarian cancer with the combination of 131I scintigraphy and 18F–FDG PET: case report and review of the literature

Study Age (y)
Gravidity
Size (cm) CA125 (U/ml) Preoperative thyroid function Imaging modalities Preoperative diagnosis Intraoperative diagnosis by frozen section Treatment
Bethune et al. 1966 [1] 62
multipara
9 × 5 × 5 1621 WNL X-ray, US, CT Suspected ovarian malignancy N/A ATH + BSO + infracolic OM
Long et al. 2001 [9] 53
multipara
15 × 11 × 7 540 N/A X-ray, US, CT Suspected ovarian malignancy Struma ovarii ATH + BSO + infracolic OM
78
multipara
12.2 × 10 × 5.2 124.9 N/A X-ray, US, CT Suspected ovarian malignancy Multilocular cysts lined by columnar epithelium ATH + BSO
Huh et al. 2002 [10] 65
multipara
5 × 4 × 4 402 Hypothyroidism US, CT Suspected ovarian malignancy Struma ovarii ATH + BSO + appendectomy + omental biopsy
Loizzi et al. 2005 [11] 65
multipara
7 × 7 161 Hyperthyroidism X-ray, CT Suspected ovarian malignancy Struma ovarii RSO
Uehara and Sawada 2007 [12] 67
N/A
About 7 2086 WNL CT Struma ovarii with Meigs’ syndrome although the ovarian tumor mimicked an advanced malignancy N/A ATH + BSO
Obeidat and Amarin 2007 [13] 52
multipara
10 × 15 × 8 149 N/A X-ray, US Suspected ovarian malignancy N/A ATH + BSO + OM
Mitrou et al. 2008 [14] 55
N/A
22 × 23 × 10 3803 N/A CT Suspected ovarian malignancy N/A ATH + BSO + infracolic OM + lymph node sampling
Rana et al. 2009 [15] 70
N/A
7.5 × 5.5 × 4 284 WNL X-ray, US, CT Suspected ovarian malignancy N/A ATH + BSO + partial OM
Jiang et al. 2010 [16] 46 multipara 20 × 18 × 15 1230.9 N/A CT Suspected ovarian malignancy Struma ovarii ATH + BSO
Obeidat and Saida 2012 [17] 55 multipara 21 × 21 × 9 872 N/A US, CT, MRI Suspected ovarian malignancy N/A Neoadjuvant chemotherapy (carboplatin and paclitaxel) followed by laparoscopic LSO for obesity
Mostaghel et al. 2012 [18] 72 multipara 9 607.4 N/A X-ray, US, CT Suspected ovarian malignancy Granulosa cell tumor ATH + BSO + OM
Jin et al. 2015 [19] 52
multipara
7 × 5 1289 N/A US, CT Suspected ovarian malignancy Cystic mature teratoma with a large component of thyroid ATH + BSO
Present 50 multipara 10 × 8 × 7 1237 WNL X-ray, US, CT, MRI, FDG PET, 123I scintigraphy Highly suggestive of struma ovarii with pseudo-Meigs’ syndrome Struma ovarii ATH + BSO