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Table 2 Literature review of struma ovarii with massive ascites and elevated CA125 levels

From: Precise preoperative diagnosis of struma ovarii with pseudo-Meigs’ syndrome mimicking ovarian cancer with the combination of 131I scintigraphy and 18F–FDG PET: case report and review of the literature

Study Age (y)
Gravidity
Size (cm) CA125 (U/ml) Preoperative thyroid function Imaging modalities Preoperative diagnosis Intraoperative diagnosis by frozen section Treatment
Leung and Hammond 1993 [21] 60
N/A
10 224 N/A US, CT Suspected ovarian malignancy Struma ovarii ATH + BSO + OM
77
N/A
8 × 10 2860 N/A US, laparoscopy Struma ovarii ATH + BSO + sampling of enlarged lymph nodes
Jotkowitz and Gee 1993 [22] 79
multipara
N/A 4670 N/A CT Suspected ovarian malignancy Adenocarcinoma ATH + BSO + OM + multiple peritoneal biopsies
Mancuso et al. 2001 [23] 31
primipara
10 × 9 689 N/A X-ray, US, MRI Suspected ovarian malignancy Struma ovarii LSO
Loizzi et al. 2002 [24] 83
multipara
10 × 7 × 6.5 1570 N/A X-ray, CT Suspected ovarian malignancy Struma ovarii ATH + BSO
Bokhari et al. 2003 [25] 51
primipara
15 × 6.5 × 11 1160 N/A MRI Suspected ovarian malignancy Struma ovarii ATH + BSO + appendectomy
Guida et al. 2005 [26] 42
multipara
12 × 8.5 × 4 2548 Hyperthyroidism X-ray, US, CT Suspected ovarian malignancy Struma ovarii ATH + BSO + sampling of swollen lymph nodes
Rim et al. 2005 [27] 50
multipara
4 × 4 attached to 3 × 3 878.67 WNL X-ray, US, CT Suspected ovarian malignancy Struma ovarii ATH + BSO
Paladini et al. 2008 [28] 42
N/A
11 × 7.3 × 8 2548 Hyperthyroidism US Suspected ovarian malignancy Struma ovarii RSO
Mui et al. 2009 [29] 56
N/A
6 × 5 × 4 coexist with 3 5218 N/A X-ray, US, CT Suspected ovarian malignancy Mature teratoma and struma ovarii ATH + BSO + OM
Peyron and Coulon 2012 [30] 78
N/A
7 164 N/A US, MRI An ovarian malignancy could not be eliminated although suspicious for struma ovarii Presence of thyroid tissue Laparoscopic LSO based on intraoperative diagnosis
Sivrioglu et al. 2013 [31] 55
N/A
3 120 WNL US, CT, MRI Suspected ovarian malignancy N/A N/A
Yadav et al. 2017 [32] 55
multipara
6 × 5 × 4.5 258 N/A X-ray, US, CT Suspected ovarian malignancy Struma ovarii LSO