Precise preoperative diagnosis of struma ovarii with pseudo-Meigs’ syndrome mimicking ovarian cancer with the combination of 131I scintigraphy and 18F–FDG PET: case report and review of the literature

Fujiwara, Sayaka; Tsuyoshi, Hideaki; Nishimura, Toshiya; Takahashi, Nozomu; Yoshida, Yoshio

doi:10.1186/s13048-018-0383-2

Table 2 Literature review of struma ovarii with massive ascites and elevated CA125 levels

From: Precise preoperative diagnosis of struma ovarii with pseudo-Meigs’ syndrome mimicking ovarian cancer with the combination of ¹³¹I scintigraphy and ¹⁸F–FDG PET: case report and review of the literature

Study	Age (y) Gravidity	Size (cm)	CA125 (U/ml)	Preoperative thyroid function	Imaging modalities	Preoperative diagnosis	Intraoperative diagnosis by frozen section	Treatment
Leung and Hammond 1993 [21]	60 N/A	10	224	N/A	US, CT	Suspected ovarian malignancy	Struma ovarii	ATH + BSO + OM
Leung and Hammond 1993 [21]	77 N/A	8 × 10	2860	N/A	US, laparoscopy	Suspected ovarian malignancy	Struma ovarii	ATH + BSO + sampling of enlarged lymph nodes
Jotkowitz and Gee 1993 [22]	79 multipara	N/A	4670	N/A	CT	Suspected ovarian malignancy	Adenocarcinoma	ATH + BSO + OM + multiple peritoneal biopsies
Mancuso et al. 2001 [23]	31 primipara	10 × 9	689	N/A	X-ray, US, MRI	Suspected ovarian malignancy	Struma ovarii	LSO
Loizzi et al. 2002 [24]	83 multipara	10 × 7 × 6.5	1570	N/A	X-ray, CT	Suspected ovarian malignancy	Struma ovarii	ATH + BSO
Bokhari et al. 2003 [25]	51 primipara	15 × 6.5 × 11	1160	N/A	MRI	Suspected ovarian malignancy	Struma ovarii	ATH + BSO + appendectomy
Guida et al. 2005 [26]	42 multipara	12 × 8.5 × 4	2548	Hyperthyroidism	X-ray, US, CT	Suspected ovarian malignancy	Struma ovarii	ATH + BSO + sampling of swollen lymph nodes
Rim et al. 2005 [27]	50 multipara	4 × 4 attached to 3 × 3	878.67	WNL	X-ray, US, CT	Suspected ovarian malignancy	Struma ovarii	ATH + BSO
Paladini et al. 2008 [28]	42 N/A	11 × 7.3 × 8	2548	Hyperthyroidism	US	Suspected ovarian malignancy	Struma ovarii	RSO
Mui et al. 2009 [29]	56 N/A	6 × 5 × 4 coexist with 3	5218	N/A	X-ray, US, CT	Suspected ovarian malignancy	Mature teratoma and struma ovarii	ATH + BSO + OM
Peyron and Coulon 2012 [30]	78 N/A	7	164	N/A	US, MRI	An ovarian malignancy could not be eliminated although suspicious for struma ovarii	Presence of thyroid tissue	Laparoscopic LSO based on intraoperative diagnosis
Sivrioglu et al. 2013 [31]	55 N/A	3	120	WNL	US, CT, MRI	Suspected ovarian malignancy	N/A	N/A
Yadav et al. 2017 [32]	55 multipara	6 × 5 × 4.5	258	N/A	X-ray, US, CT	Suspected ovarian malignancy	Struma ovarii	LSO

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