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Fig. 7 | Journal of Ovarian Research

Fig. 7

From: Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death

Fig. 7

ST6Gal-I activity protects cancer cells against gefitinib-mediated apoptosis. a. OV4 EV or OE cells and b. BxPC3 EV or KD cells were treated with gefitinib for 24, 48 and 72 h and analyzed for apoptosis via a luminescence assay that detects caspase 3 and 7 activity. Caspase activity in geftinib-treated cells was normalized to caspase activity in untreated cells. Data shown are from a representative experiment, with at least 2 independent experiments performed for each cell line. Graph depicts means ± S.D

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Journal of Ovarian Research

ISSN: 1757-2215

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