Skip to main content

Table 1 The included papers

From: Neurofibroma involving obturator nerve mimicking an adnexal mass: a rare case report and PRISMA-driven systematic review

Author Year of publication Gender Age Tumor location Symptoms Surgical intervention Prognosis Image study/Genetic analysis Immunohistochemistry stain
Topsakal et al. [4] 2001 female 35 Right pre-sacral solitary neurofibroma Bilateral sciatica radiating to the right inguinal and lumbar area for 2 years Extra-peritoneal approach through a right J incision with complete resection Uneventful without neurological deficit Transvaginal ultrasound, Computed Tomography / Without gene of neurofibromatosis Vimentin (+), Fibronectin(+), S-100(−), Cytokeratin(−), Desmin(−)
Kim et al. [5] 2013 female 72 Early gastric cancer with a 1.6-cm sized neurofibroma posterior to duodenum Epigastric discomfort for 2 months Laparoscopic assisted distal gastrectomy and retro-pancreatic nodal dissection Uneventful without neurological deficit Abdominal Computed Tomography / Without gene of neurofibromatosis S-100 (+)
Dafford et al. [6] 2007 Total 38 patients Total 38 patients Pelvic retroperitoneal region Pelvic pain, paresthesia or weakness, palpable pelvic mass Total or subtotal resection Moderate pain reduction Magnetic resonance imaging, Computed Tomography / Without gene of neurofibromatosis S-100 (+)
Shen et al. [7] 2016 female 45 Giant neurofibroma involving the pelvic cavity, retroperitoneal space and right buttock Compressive displacement of abdominal and pelvic organs En-bloc abdominopelvic tumor removal Uneventful without neurological deficit Computed Tomography / Not mention Vimentin (+), CD-34(+), S-100(−), smooth muscle actin(−), desmin(−), cytokeratin(−)
Ishikawa et al. [8] 1989 female 56 Retro-vesical space Dysuria for 2 years, traction pain in the left lower limb Exploratory laparotomy Uneventful without neurological deficit Computed Tomography / Not mention S-100 (+), neuron specific enolase(NSE) (+)
Hunter et al. [9] 1988 female 34 Pulsatile mass at the right pelvic side-wall Right lower pelvic pain with sharp radiation into the right lower extremity for 3 years Total tumor excision, right side J incision with extra-peritoneal approach Loss of range of motion in the right foot, receiving physical therapy and improvement after 7 month of surgery Intravenous pyelogram, cystoscopy / Not mention Not mention
Cowles et al. [10] 1987 female 25 Soft mass extending from pubo-coccygeus muscle and para-vaginal space Mild pelvic discomfort for one year exacerbated by prolong sitting Surgical exploration and total excision Uneventful without neurological deficit Not mention / Not mention Not mention
Gupta et al. [11] 2015 female 51 Over the left adrenal gland Upper abdominal pain for 2 years Laparoscopic left adrenalectomy Uneventful without neurological deficit Computed Tomography / Without gene of neurofibromatosis S-100 (+)