Table 2 Gives NIH consensus guidelines for type I neurofibromatosis diagnostic criteria
NIH consensus guidelines: diagnostic criteria for neurofibromatosis I. Two or more of the following | Â |
|---|---|
1. Six or more cafe’-au-lait macules that are (in greatest diameter) > 5 mm in pre-pubertal individuals > 15 mm in post-pubertal individuals |  |
2. Two or more neurofibromas of any type, or one plexiform neurofibroma | Â |
3. Axillary/inguinal freckling | Â |
4. Optic glioma | Â |
5. Two or more Lisch nodules | Â |
6. Distinctive osseous lesion (i.e. sphenoid dysplasia or thinning of long bone cortex with or without pseudoarthrosis) | Â |
7. First degree relative with NF-1 | Â |