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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: Metformin improves ovarian follicle dynamics by reducing theca cell proliferation and CYP-17 expression in an androgenized rat model

Fig. 2

Photomicrographs of ovary sections immunostained for VEGFA (a, b, c); note the higher level of staining in the inner theca and granulosa cells in the GA group (b). Ki67 (e, f, g) staining was highest in the inner theca of the GA group (f) and lowest in the granulosa cells of the control group (e). CYP17 (i, j, k) expression was highest in the inner theca of the GA (j) group and in the granulosa cells of the control group (i). d, h, and l are negative controls for VEGFA, Ki67 and CYP17, respectively. Arrows: inner theca; asterisks: granulosa cells. Bars = 20 mm; magnification × 400

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