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Table 1 Clinicopathologic characteristics of the patients according to the route of disease spread (n = 179)

From: Does the primary route of spread have a prognostic significance in stage III non-serous epithelial ovarian cancer?

 

RP Group

(n = 35)

IP Group

(n = 72)

IP/RP Group

(n = 72)

p

Age (median, range)

50 (18-74)

54 (28-78)

54 (27-77)

0.18

Menopausal Status (n, %)

   

0.23

 Premenopausal

18 (51.4)

25 (34.7)

27 (37.5)

 

 Postmenopausal

17 (48.6)

47 (65.3)

45 (62.5)

 

Histology (n, %)

   

0.42

 Endometrioid

12 (34.3)

23 (31.9)

17 (23.6)

 

 Clear-cell

10 (28.6)

15 (20.8)

23 (31.9)

 

 Mucinous

10 (28.6)

24 (33.3)

13 (18.1)

 

 Mixed

3 (8.6)

10 (13.9)

19 (26.4)

 

Gradea (n, %)

   

0.078

 1

5 (20)

8 (14)

6 (12.2)

 

 2

9 (36)

26 (45.6)

10 (20.4)

 

 3

11 (44)

23(40.4)

3 (67.3)

 

Baseline Serum CA 125

(u/mL) (median, range)

118 (10-3305)

200 (11-9523)

400 (10-11,779)

0.001 b

Tumor size (cm)

(median, range)

12 (4-30)

10 (3-39)

10 (3-40)

0.27

Ascites (n, %)

   

0.001 b

 Yes

12 (34.3)

37 (51.4)

51 (70.8)

 

 No

23 (65.7)

35 (48.6)

21 (29.2)

 

Peritoneal cytology (n, %)

   

< 0.001 b

 Positive

12 (34.3)

53 (73.6)

53 (73.6)

 

 Negative

23 (65.7)

19 (26.4)

19 (26.4)

 

Bilaterality

   

0.002 b

 Yes

10 (28.6)

28 (38.9)

44 (61.1)

 

 No

25 (71.4)

44 (61.1)

28 (38.9)

 

Total number of LNs removed

(median, range)

43 (15-105)

37.5 (15-93)

40 (15-103)

0.71

Number of pelvic LNs removed

(median, range)

25 (10-93)

28.5 (10-75)

28.5 (10-71)

0.97

Number of para-aortic LNs removed

(median, range)

11 (5-46)

8.5 (5-45)

10 (5-54)

0.57

CRS

   

0.009

 Optimal

17 (48.6)

17(30.9)

17(30.9)

 

 Maximal

18 (51.4)

55(69.1)

55(69.1)

 
  1. Abbreviations: RP retroperitoneal only disease, IP intraperitoneal only disease, IP/RP combination of intraperitoneal and retroperitoneal disease, n number, LN lymph node, CRS cytoreductive surgery
  2. aPatients with clear-cell histology were excluded from the statistical analysis
  3. bp values in bold characteristics refer to statistical significance