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Table 3 Univariate and multivariate analyses for overall survival in women with ovarian non-serous carcinoma

From: Does the primary route of spread have a prognostic significance in stage III non-serous epithelial ovarian cancer?

 

OSa

Eventsb

Univariate

Multivariate

p

HR

CI 95%

p

Age, y

  ≤53

61.5%

29/87 (33.3%)

0.004

   

  > 53

40.9%

51/92 (55.4%)

    

Menopausal Status

 Premenopausal

66.4%

21/70 (30%)

0.001

   

 Postmenopausal

40.8%

59/109 (54.1%)

    

Histologic type

 Clear

40.4%

26/48 (54.1%)

0.335

   

 Müsinöz

55.8%

23/47 (48.9%)

    

 Endometrioid

51.7%

21/52 (40.4%)

    

 Mixt

59.9%

10/32 (31.2%)

    

Route of Spread

 Intraperitoneal

54%

31/72 (43%)

0.011

   

 Retroperitoneal

74.4%

10/35 (28.6%)

    

 Intra+Retroperitoneal

36%

39/72 (54.1%)

    

Peritoneal cytology

 Positive

50.5%

51/118 (43.2%)

0.987

   

 Negative

51.1%

29/61 (47.5%)

    

Bilateralty

 Unilateral

59.7%

40/97 (41.2%)

0.293

   

 Bilateral

40.2%

40/82 (48.7%)

    

Tumor size(cm)

  < 10

47.7%

38/78 (48.7%)

0.169

   

  ≥ 10

53.5%

42/101 (41.6%)

    

CA-125(IU/ml)

  < 250

56.2%

39/88 (44.3%)

0.690

   

  ≥ 250

44.5%

39/84 (46.4%)

    

Ascites

 Yes

45.4%

50/100 (50%)

0.150

   

 No

58.1%

30/79 (37.9%)

    

LN involvement

 Yes

49%

49/107 (45.8%)

0.955

   

 No

54%

31/72 (43%)

    

Omental involvement

 Yes

38.9%

57/106 (53.7%)

0.001

   

 No

66.8%

22/71 (30.9%)

    

Grade

 G1-2

69%

19/69 (27.5%)

0.003

1.9

1.071-3.421

0.028

 G3

42%

35/67 (52.2%)

    

CRS

 Maximal

94.5%

4/51 (7.8%)

< 0.001

5.5

1.968-15.625

0.001

 Optimal

36.2%

76/128 (59.3%)

    
  1. Characters in bold indicate statistical significance
  2. Abbreviations: OS overall survival, LN lymph node, CRS cytoreductive surgery
  3. a5-year overall survival
  4. bThe number of cases with death