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Fig. 3 | Journal of Ovarian Research

Fig. 3

From: Pioglitazone is effective for multiple phenotyepes of the Zucker fa/fa rat with polycystc ovary morphology and insulin resistance

Fig. 3

Ovarian histology of atretic follicles detected by the TUNEL method, and total follicle numbers, atretic follicle numbers and rates of atretic follicles of control rats (Zucker +/+ rats), PCO model rats (Zucker fa/fa rats) and pitoglitazone-treated PCO model rats. The TUNEL method and follicle counts of these rats were performed on day 15 in control rats (a), PCO model rats (b) and Pioglitazone treated PCO model rats (c) (the day the rats were killed). Follicles were classified as atretic ▲ if they had five or more apoptic granulosa cells [23]. Values are means±SD, *P < 0.05 v.s. control rats. **P, 0.05 v.s. control rats, Pioglitazone treated PCO model rats

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