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Table 1 Patient and IVF cycle characteristics in women above age 43 with VER, ER and SR

From: With low ovarian reserve, Highly Individualized Egg Retrieval (HIER) improves IVF results by avoiding premature luteinization

 

VER (13.5–15.5 mm)

ER (16.0–18.0 mm)

SR (18.5–20.5 mm)

Number of Patients

17

24

15

Average age (years)

44.9 ± 0.3

44.6 ± 0.3

45.0 ± 0.6

FSH (mIU/ml)

12.6 ± 3.3

9.3 ± 1.0

12.8 ± 5.9

AMH (ng/ml)

0.7 ± 0.2

0.8 ± 0.1

1.1 ± 0.3

P4/E2 ratio on hCG trigger day

2.3 ± 0.3

2.0 ± 0.3

2.1 ± 0.3

Retrieved oocytes

3.9 ± 0.6

5.6 ± 0.8

4.8 ± 1.0

Mature oocytes

2.0 ± 0.5

3.4 ± 0.5

2.4 ± 0.8

% of mature oocytes

53.5 ± 8.7

66.0 ± 5.5

51.1 ± 10.5

Immature oocytes

1.7 ± 0.4

1.4 ± 0.3

2.0 ± 0.8

% of immature oocytes

41.5 ± 8.2

22.8 ± 5.1

43.9 ± 10.5

Atretic oocyte/patient

0.3 ± 0.1

0.8 ± 0.3

0.3 ± 0.2

% of atretic oocyte

7.4 ± 3.6

11.2 ± 3.5

4.8 ± 2.6

Fertilized oocytes

2.3 ± 0.4

3.0 ± 0.5

2.9 ± 0.6

Total transferable embryos

2.0 ± 0.3

2.7 ± 0.4

2.3 ± 0.6

High quality embryos

0.9 ± 0.1a

2.3 ± 0.4b

0.7 ± 0.2a

% of high quality embryos

52.3 ± 8.7a

83.8 ± 5.8b

34.0 ± 13.2a

Pregnant rate

5.9% (1/17)a

16.7% (4/24)b

6.7% (1/15)a

  1. VER, very early retrieval; ER, early retrieval; SR, standard retrieval; a/adenotes no significant difference; a/bdenotes significant difference