Table 3 Reactome network analysis revealing significant association with mitotic regulation
Associated Pathway | Genes | FDR |
|---|---|---|
mitotic pro metaphase | CCNB1, CKAP5, BUB1, CENPF, CENPE, NDC80 | FDR ≤ 3.33 x 10-4 |
mitotic metaphase and anaphase | CKAP5, LMNA, BUB1, CENPF, CENPE, NDC80, UBE2C, PSME1 | FDR ≤ 1.00 x 10-3 |
mitotic G2-G2/M phase | CCNB1, CKAP5, NEK2, CENPF, AURKA | FDR ≤ 1.00 x 10-3 |
APC/C-mediated degradation of cell cycle proteins | AURKA, UBE2C, CCNB1, PSME1 | FDR ≤ 4.80 x 10-3 |