ClinicalTrials.gov studies | Not-for-profit 2008–2015 (274) | Profit 2008–2015 (224) | ||
---|---|---|---|---|
N | % | N | % | |
Study phase | ||||
0 | 3 | 16.5 | – | – |
I | 46 | 19.0 | 73 | 33.2 |
I-II | 18 | 7.4 | 15 | 6.8 |
II | 103 | 42.6 | 96 | 43.6 |
II-III | – | – | 4 | 1.8 |
III | 29 | 12.0 | 17 | 7.7 |
IV | 3 | 1.2 | 2 | 0.9 |
Observational | 40 | 16.5 | 13 | 5.9 |
Missing | 32 | 4 | ||
Center | ||||
Multicenter | 125 | 58.7 | 162 | 78.6 |
Single-center | 88 | 41.3 | 44 | 21.4 |
Missing | 61 | 18 | ||
Country | ||||
America | 178 | 66.4 | 116 | 53.5 |
Europe | 64 | 23.9 | 25 | 11.5 |
International | 16 | 6.0 | 66 | 30.4 |
Asia | 8 | 3.0 | 9 | 4.2 |
Oceania | 2 | 0.8 | 1 | 0.5 |
Study purpose | ||||
Treatment | 196 | 76.0 | 203 | 92.7 |
Prevention and screening | 10 | 3.9 | 4 | 1.8 |
Diagnostic | 8 | 3.1 | 5 | 2.3 |
Supportive care | 15 | 5.8 | 2 | 0.9 |
Health services research | 3 | 1.2 | 1 | 0.5 |
Other | 26 | 10.1 | 4 | 1.8 |
Missing | 16 | |||
Endpoint classification | ||||
Efficacy | 71 | 32.0 | 30 | 14.4 |
Safety | 18 | 8.1 | 35 | 16.8 |
Safety and efficacy | 78 | 35.1 | 110 | 52.9 |
Other | 55 | 24.8 | 33 | 15.9 |
Missing | 52 | 16 | ||
Study duration (years) - Mean (SD) | 5.27 (3.00) | 3.74 (2.17) | ||
Number of subjects | ||||
< 50 | 128 | 46.7 | 112 | 50.0 |
> =50 | 143 | 52.2 | 111 | 49.5 |