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Table 4 Comparison of KLK10 exon 3 unmethylated PCR product concentration (ng/μl) according to patient age

From: KLK10 exon 3 unmethylated PCR product concentration: a new potential early diagnostic marker in ovarian cancer? - A pilot study

KLK10 exon 3 unmethylated PCR product; ng/μl, mean ± SD

Age group

p-value

16–32 years

33–55 years

>  55 years

Overall samples (n = 6–27)

0.032 ± 0.029

0.064 ± 0.029

0.090 ± 0.037

0.004b

Benign patients:

 Normal ovary (n = 0–5)

–

0.078 ± 0.034

0.135 ± 0.007

0.078b

 Benign ovary (n = 2–10)

0.060 ± 0.042

0.078 ± 0.034

0.090 ± 0.056

0.728b

p-value

–

1.00a

0.380a

 

Malignant patients:

 Normal ovary (n = 1–3)

0.020 ± −

0.040 ± 0.000

0.070 ± 0.042

0.335b

 Malignant ovary (n = 3–9)

0.017 ± 0.011

0.049 ± 0.010

0.073 ± 0.015

0.000b

p-value

0.826a

0.188a

0.903a

 
  1. - no samples or statistical test not applicable, SD standard deviation
  2. aStudent t-test
  3. bANOVA test