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Table 5 Comparison of KLK10 exon 3 unmethylated PCR product concentration (ng/μl) according to preoperative serum KLK10

From: KLK10 exon 3 unmethylated PCR product concentration: a new potential early diagnostic marker in ovarian cancer? - A pilot study

KLK10 exon 3 unmethylated PCR product; ng/μl, mean ± SD

Serum KLK10

p-value

< 2 ng/ml

≥ 2 ng/ml

Overall samples (n = 15–27)

0.075 ± 0.038

0.046 ± 0.018

0.007a

Benign patients:

 Normal ovary (n = 1–6)

0.100 ± 0.040

0.060 ± −

0.397a

 Benign ovary (n = 3–11)

0.086 ± 0.033

0.043 ± 0.023

0.060a

p-value

0.463a

0.596a

 

Malignant patients:

 Normal ovary (n = 2–4)

0.070 ± 0.042

0.035 ± 0.010

0.153a

 Malignant ovary (n = 7–8)

0.044 ± 0.023

0.051 ± 0.019

0.511a

p-value

0.252a

0.156a

 
  1. - not applicable, SD standard deviation
  2. aStudent t-test