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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: MicroRNA-424/503 cluster members regulate bovine granulosa cell proliferation and cell cycle progression by targeting SMAD7 gene through activin signalling pathway

Fig. 2

SMAD7 and ACVR2A are the direct targets of the miR-424/503 cluster members. Relative luciferase activity in bovine granulosa cells co-transfected with pmiRGLO vector harbouring the wild-type (WT) or mutant (MT) 3´-UTR sequence of SMAD7 or ACVR2A and the corresponding miRNA mimics or negative controls (NC) for miR-424 and miR-503. The data are presented as the mean ± SEM (*p < 0.05, **p < 0.01)

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